Annali dell'Istituto Superiore di Sanità
Print version ISSN 0021-2571
BENEDETTI, Marta et al. No evidence of increased risk of soft tissue sarcomas in the neighborhood of a steel foundry in Verona. Ann. Ist. Super. Sanità [online]. 2010, vol.46, n.4, pp. 360-365. ISSN 0021-2571. http://dx.doi.org/10.4415/ANN_10_04_03.
The aim of the present study was to evaluate the possible association between occurrence of soft tissue sarcomas in Verona (Italy) and residence near a steel foundry, whose emissions of dioxin-like compounds may be relevant. Exposure to total suspended particulate (TSP) emitted from the plant as estimated by ADMS-urban dispersion model was used as an indirect index of exposure to dioxin-like compounds. Verona municipality was divided in six subareas according to the decreasing levels of estimated TSP exposure, and soft tissue sarcomas cases were mapped according to residence at time of diagnosis. Standardized incidence ratios were computed. No statistically significant departures between observed and expected cases were detected as illustrated by trend-test results.
Keywords : sarcoma; dioxins; environmental exposure; epidemiology.