Annali dell'Istituto Superiore di Sanità
Print version ISSN 0021-2571
FAZZO, Lucia et al. Ecological studies of cancer incidence in an area interested by dumping waste sites in Campania (Italy). Ann. Ist. Super. Sanità [online]. 2011, vol.47, n.2, pp. 181-191. ISSN 0021-2571. http://dx.doi.org/10.4415/ANN_11_02_10.
Cancer incidence was investigated in an area which has been affected by the illegal practices of dumping hazardous waste and setting fire to mismanaged waste. For the 35 municipalities of this area that are served by a Cancer Registry, municipal standardized incidence ratios (SIR) and hierarchical Bayesian estimators (BIR) were computed. Moreover, municipal spatial clustering and a Poisson regression by municipality index of waste-related exposure were performed for 10 cancer types. Increased municipality SIRs were found for some cancer types. The BIRs confirmed the increases for liver cancer in two municipalities. Statistically significant clusters were detected for liver, lung, leukaemia and soft tissue sarcomas. In the regression analysis, testis cancer showed significant trend with the index of waste-related exposure (RR = 1.18).
Keywords : cancer incidence; waste dumping sites; testicular neoplasms; liver neoplasms.