Revista de Saúde Pública
On-line version ISSN 1518-8787
FERRARONI, José J.. Minocycline treatment of chloroquine-and Fansidar R-resistant falciparum malarial. Rev. Saúde Pública [online]. 1983, vol.17, n.4, pp. 328-331. ISSN 1518-8787. http://dx.doi.org/10.1590/S0034-89101983000400007.
In April 1978, a Plasmodium falciparum infection was diagnosed in an adult male in Brazilian Amazonia. The parasite was resistant in vitro to chloroquine and resistent in vivo to pyrimethamine-sulfadoxine (FansidarR). The patient was successfully treated with minocycline (MinomaxR); however, his immune response to the parasite may have played an important role in the efficacy of the minocycline treatment.
Keywords : Plasmodium falciparum; Malaria [treatment]; Tetracyclines.