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Revista de Saúde Pública

On-line version ISSN 1518-8787Print version ISSN 0034-8910


PEDROZO, Maria de Fatima M.  and  SIQUEIRA, Maria Elisa P. B.. Spectrophotometric and gas chromatographic determination of trichloroacetic acid in urine. Rev. Saúde Pública [online]. 1996, vol.30, n.3, pp.261-266. ISSN 1518-8787.

Some chlorinated hydrocarbon solvents ¾ 1,1,1-trichloroethane, tricloroethylene and perchloroethylene ¾ have a common biotransformation product, trichloroacetic acid, which can be used as their biological exposure index. The spectrophotometric and gas chromatographic methods for the determination of trichloroacetic acid were studied and used as well as in its determination in the urine of workers exposed to 1,1,1-trichloroethane . Both methods showed good precision and no statistically significant difference was found although the gas cromatographic method presented a lower detection limit.

Keywords : Trichloroacetic acid [utine]; Spectrophotometry [utilization]; Chromatography [utilization].

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