Revista de Saúde Pública
On-line version ISSN 1518-8787Print version ISSN 0034-8910
TOMINAGA, Maria Y and MIDIO, Antonio F. Human exposure to trihalomethanes in drinking water. Rev. Saúde Pública [online]. 1999, vol.33, n.4, pp.413-421. ISSN 1518-8787. http://dx.doi.org/10.1590/S0034-89101999000400013.
Halogenated hydrocarbon compounds, some of them recognized as carcinogenic to different animal species can be found in drinking water. Chloroform, bromodichloromethane, dibromochloromethane and bromoform are the most important trihalomethanes found in potable water. They are produced in natural waters during chlorinated desinfection by the halogenation of precursors, specially humic and fulvic compounds. The review, in the MEDLINE covers the period from 1974 to 1998, presents the general aspects of the formation of trihalomethanes, sources of human exposure and their toxicological meaning for exposed organisms: toxicokinetic disposition and spectrum of toxic effects (carcinogenic, mutagenic and teratogenic).
Keywords : Trihalomethanes; Potable water [analysis]; Toxicology.