Abstract

PEREZ-GUTIERREZ, Rosa Martha; PEREZ-GONZALEZ, Cuauhtémoc; ZAVALA-SANCHEZ, Miguel Angel  and  PEREZ-GUTIERREZ, Salud. Hypoglicemic activity of Bouvardia terniflora, Brickellia veronicaefolia and Parmentiera edulis. Salud pública Méx [online]. 1998, vol.40, n.4, pp. 354-358. ISSN 0036-3634.  http://dx.doi.org/10.1590/S0036-36341998000400008.

Objective. To evaluate the hypoglycemic activity of the hexane, chloroform and methanol extracts of Bouvardia terniflora, Brickelia veronicaefolia and Parmentiera edulis. Material and methods. Normal and alloxan-induced diabetic mice were administered these plant extracts (intraperitoneal 100, 200 and 300 mg/kg). Results. The administration of 300 mg/kg of chloroform extracts from P. edulis and B. terniflora and hexane from B. veronicaefolia to diabetic mice decreased the blood glucose levels in 43.75, 58.56 and 72.13%, respectively. These extracts administered to normal mice reduced blood glucose levels in 29.61, 33.42 and 39.84%, respectively. Conclusions. The hypoglycemic effect of these plant extracts used in traditional medicine for diabetes treatment is confirmed.

Keywords : hypoglycemic; plants [medicinal]; Brickellia veronicaefolia; Bouvardia terniflora; Parmentiera edulis.