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Salud Pública de México

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RODRIGUEZ, Romeo S.; CALDERON-JAIMES, Ernesto; GOMEZ-BARRETO, Demóstenes  and  ESPINOSA-DE LOS MONTEROS, Luz Elena. Antimicrobial resistance of Streptococcus pyogenes clinical strains. Salud pública Méx [online]. 2000, vol.42, n.3, pp.226-229. ISSN 0036-3634.

OBJECTIVE: To determine the antibiotic susceptibility of recent isolates of Streptococcus pyogenes and to evaluate the prevalence of macrolide-resistant phenotypes. MATERIAL AND METHODS: In 1999, we conducted a cross-sectional study at Mexico Children's Hospital "Federico Gomez", to analyze one hundred strains of S. pyogenes isolated from 1992 to 1998, in children with uncomplicated pharyngotonsillitis. Strains were frozen at the bacteriology lab until they were analyzed. Strains were tested for susceptibility against some b-lactams, macrolides and clindamycin. Double-disk testing was carried out to evaluate erythromycin-resistant phenotypes. Data are presented using central tendency measures. RESULTS: All tested strains were not resistant to b-lactams and clindamycin; 16% of the strains were resistant to macrolides and all of them belonged to phenotype M. CONCLUSIONS: Susceptibility testing is recommended to identify possible changes in antibiotic resistance to streptococci.

Keywords : Streptococcus pyogenes [drug resistance]; microbial; hospitals; public; hospitals; pediatric; Mexico.

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