SciELO - Scientific Electronic Library Online

vol.50 issue2Prognostic factors related to breast cancer survival author indexsubject indexarticles search
Home Page  

Services on Demand




Related links


Salud Pública de México

Print version ISSN 0036-3634


GUTIERREZ-DELGADO, Cristina et al. Generalized cost-effectiveness of preventive interventions against cervical cancer in Mexican women: results of a Markov model from the public sector perspective. Salud pública Méx [online]. 2008, vol.50, n.2, pp.107-118. ISSN 0036-3634.

OBJECTIVE: To develop a generalized cost-effectiveness analysis (GCEA) of the HPV vaccine, hybrid capture screening (HC) and Papanicolaou screening (Pap) in the Mexican context. MATERIALS AND METHODS: From April to August 2007, in Mexico, a GCEA of the interventions was developed for 10 possible scenarios using a Markov model from the public sector perspective as payer. RESULTS: Scenarios considering 80% coverage show an ACER per DALY averted of $16678 pesos for Pap of women between ages 25 and 64, $17277 pesos for HC of women between ages 30 and 64, and $84008 pesos for vaccination of 12-year-old girls. Annual financing of $621, $741 and $2255 million pesos, respectively, is needed for these scenarios. CONCLUSIONS: A selective, combined introduction of Pap-HC screening that considers the comparative advantages of application in different populations and geographical areas is suggested. Additionally, it is suggested to introduce the vaccine once a threshold price of $181 pesos per dose -when the vaccine becomes equal in terms of cost-effectiveness to HC- has been achieved.

Keywords : cervical cancer; cost-effectiveness; financing; cervical screening; HVP vaccine.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )