Bulletin of the World Health Organization
Print version ISSN 0042-9686
FALLAH, Mohammad; MIRARAB, Akbar; JAMALIAN, Farzad and GHADERI, Ahmad. Evaluation of two years of mass chemotherapy against ascariasis in Hamadan, Islamic Republic of Iran. Bull World Health Organ [online]. 2002, vol.80, n.5, pp. 399-402. ISSN 0042-9686. http://dx.doi.org/10.1590/S0042-96862002000500011.
OBJECTIVE: To evaluate the mass treatment of ascariasis in rural areas of Hamadan Province, Islamic Republic of Iran. METHODS: A control programme in rural areas of Hamadan Province, which began in November 1997, involved giving all persons a single dose of 400 mg albendazole at intervals of three months. The efficacy of the treatment was evaluated by the formalin-ether concentration technique for stool examination and by the Stoll quantitative method. FINDINGS: The average rate of infection with Ascaris before treatment was 53.3%, ranging from 40% in Hamadan district to 75% in Toysercan. Two areas, Malayer and Nahavand, were excluded from the programme because the infection rates were only 13% and 4%, respectively. After two years of mass treatment the infection rate had decreased to 6%. The proportion of positive cases excreting only unfertilized eggs increased to 32%. No side-effects of mass treatment were observed. CONCLUSION: Systematic mass treatment giving high coverage proved to be very effective in the control of ascariasis, notwithstanding a lack of other preventive measures.
Keywords : Ascariasis [drug therapy]; Albendazole [therapeutic use]; Ascaris lumbricoides [pathogenicity]; Trichuris [pathogenicity]; Giardia lamblia [pathogenicity]; Hymenolepis [pathogenicity]; Treatment outcome; Iran.