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Cadernos de Saúde Pública

On-line version ISSN 1678-4464Print version ISSN 0102-311X


BAIOCHI, Eduardo; CAMANO, Luiz  and  BORDIN, José Orlando. Evaluation of fetomaternal hemorrhage in postpartum patients with indication for administration of anti-D immunoglobulin. Cad. Saúde Pública [online]. 2005, vol.21, n.5, pp.1357-1365. ISSN 1678-4464.

This study evaluated fetomaternal hemorrhage (FMH) in 343 postpartum patients who required prophylaxis of Rh alloimmunization with anti-D immunoglobulin. The rosette test was applied to screen for patients needing quantitative determination of fetal blood transferred from the maternal circulation, which was then measured by the Kleihauer-Betke test (K-B). The rosette test was positive in 22 cases (6.4%). In five of these cases, K-B did not show fetomaternal hemorrhage (a 1.45% false-positive rate for the rosette test), and in one case the test was inconclusive. There were 8 cases with FMH < 10ml (2.3%), 6 cases with FMH from 10 to 30ml (1.7%), and two cases with FMH > 30ml (0.58%), requiring a supplementary dose of anti-D. The study concludes that following the rosette test, additional evaluation of FMH using a quantitative test was unnecessary in 93.6% of the cases.

Keywords : Fetal Erythroblastosis; Fetomaternal Transfusion; Rho(D) Immune Globulin.

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