Abstract

MONTEIRO, Denise Leite Maia; TRAJANO, Alexandre José Baptista; SILVA, Kátia Silveira da  and  RUSSOMANO, Fábio Bastos. Pre-invasive cervical disease and uterine cervical cancer in Brazilian adolescents: prevalence and related factors. Cad. Saúde Pública [online]. 2006, vol.22, n.12, pp. 2439-2548. ISSN 0102-311X.  http://dx.doi.org/10.1590/S0102-311X2006001200004.

The objective was to describe the prevalence and factors associated with uterine cervical cancer (CA) and high-grade squamous intraepithelial lesions (HSIL) in adolescents. A cross-sectional study was carried out with 702 sexually active adolescents treated at a general hospital in Rio de Janeiro, Brazil, from 1993 to 2002. Screening was performed by cytopathology and colposcopy and confirmation by biopsy. Exposure variables were socio-demographic characteristics and those related to reproductive health, habits, and sexual behavior. Adjusted odds ratios were estimated using multivariate logistic regression analysis. Based on histopathology, the prevalence of HSIL/CA was 3% (95%CI: 1.8-4.6). There was one case of invasive cancer. With each additional pregnancy, the odds of HSIL/CA increased by 2.2 (95%CI: 1.1-4.4). Age was also associated with this outcome, doubling the odds of acquiring this degree of disease with each year of age (OR = 2.0; 95%CI: 1.2-3.4). The prevalence of lesions suggests the importance of including sexually active adolescent females in cervical cancer screening programs aimed at early detection and treatment of these lesions.

Keywords : Uterine Cervical Neoplasms; Human Papillomavirus; Adolescent.