Cadernos de Saúde Pública
On-line version ISSN 1678-4464
Print version ISSN 0102-311X
ASSUNCAO, Maria Cecília F. and SANTOS, Iná S.. Effect of food fortification with iron on childhood anemia: a review study. Cad. Saúde Pública [online]. 2007, vol.23, n.2, pp.269-281. ISSN 1678-4464. http://dx.doi.org/10.1590/S0102-311X2007000200003.
A systematic review was conducted to identify studies assessing the effect of food fortification with iron on childhood anemia. The MEDLINE, LILACS, and PubMed databases and WHO and PAHO sites were searched with no time limitation, including articles published in Portuguese, English, or Spanish, using the following key words and their combination: food fortification, iron, effectiveness, efficacy, anemia, flour, staple foods, interventions, and children. Of 21 studies reviewed, only one failed to report a positive, favorable effect of iron fortification, indicating the possibility of publication bias. The studies showed important methodological limitations. The two studies with the best methodological scores showed opposite results, highlighting the need for larger trials with better planning to explore this hypothesis.
Keywords : Fortified Food; Iron; Anemia; Child Welfare.