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Cadernos de Saúde Pública

On-line version ISSN 1678-4464Print version ISSN 0102-311X


PAULA, Glaucio de Moraes; SILVA, Luiz Guilherme Pessoa da; MOREIRA, Maria Elizabeth Lopes  and  BONFIM, Olga. Repercussions of premature rupture of fetal membranes on neonatal morbidity and mortality. Cad. Saúde Pública [online]. 2008, vol.24, n.11, pp.2521-2531. ISSN 1678-4464.

The objective of this study was to analyze factors associated with death and survival with sequelae in neonates after premature rupture of fetal membranes (PROM). An observational historical cohort study analyzed charts of patients with PROM at < 34 weeks gestation. The variables were compared with neonatal death and survival with sequelae as the outcomes. In both groups, the data were submitted to bivariate analysis, and the variables showing significance were submitted to logistic regression. The final multivariate model for fetal death showed statistical significance for the following: chorioamnionitis; 5-minute Apgar score < 5; birth weight < 1,000g; and cardiopulmonary resuscitation. Survival with sequela was associated with: cervical colonization; patent ductus arteriosus; 5-minute Apgar score < 5; and birth weight < 1,000g. Infections, very low birth weight, and peripartum asphyxia were the principal variables associated with the target outcomes among newborns from gestations involving PROM.

Keywords : Premature Rupture Fetal Membranes; Neonatal Mortality [Public Health]; Morbidity.

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