Revista de Salud Pública
Print version ISSN 0124-0064
ALEMAN, Ader et al. First serological evidence of Hantavirus infection in rodents in Colombia. Rev. salud pública [online]. 2006, vol.8, suppl.1, pp.1-12. ISSN 0124-0064. http://dx.doi.org/10.1590/S0124-00642006000400001.
OBJECTIVE: Determining Hantavirus infection prevalence in rodents in the Córdoba department, Colombia. METHODS: Rodents were captured using Sherman live-capture traps (8x9x23 cm; Sherman Traps, Inc., Tallahassee, FL) in peridomestic areas of Córdoba. Hantavirus IgG antibodies were detected by ELISA using Sin Nombre virus (SNV) recombinant nucleocapsid antigen (CDC, Atlanta, Georgia, USA). RESULTS: 336 rodents were captured in 11 townships in the Córdoba department (Murinae: 249; Sigmodontinae: 68; Heteromyidae: 17; Echimyidae: 2; 8,5 % overall trap success) during 79 nights of trapping between January 2003 and November 2004. Hantavirus antibody seroprevalence was 2,1 % (7 out of 336 captures). Prevalence by genus varied between 5,9 % (1 out of 17 Heteromys) to 50 % (1 out of 2 Proechimys). CONCLUSIONS: SNV-reactive antibody prevalence in rodents in Córdoba, Colombia, indicated that at least one hantavirus is endemic in rodents in northern Colombia and is frequently transmitted to rural residents.
Keywords : Hantavirus; rodent; Colombia; seroprevalence.