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Gaceta Sanitaria

Print version ISSN 0213-9111

Abstract

CARRACEDO-MARTINEZ, Eduardo  and  PIA-MORANDEIRA, Agustín. Impact of a health safety warning on strontium ranelate utilization. Gac Sanit [online]. 2010, vol.24, n.2, pp.151-153. ISSN 0213-9111.  http://dx.doi.org/10.1590/S0213-91112010000200011.

Objective: To evaluate changes in the use of strontium ranelate following a health safety warning in November 2007 on the risks of the development of DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) with the use of this medicine. Method: Monthly strontium ranelate DHD (daily defined doses/1,000 inhabitants/day) were calculated between 2006 and 2008 in a health area of Spain. The data were analyzed graphically and through a multiple regression model. Results: Graphical representation showed a long-term rising trend throughout the study period, although growth slowed after the safety warning was issued. The multiple regression model showed that the health warning was statistically significant. Conclusion: The use of strontium ranelate continues to grow after the issue of the health safety warning, although at a slower pace than previously.

Keywords : Strontium ranelate; Osteoporosis; Drug utilization.

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