SciELO - Scientific Electronic Library Online

vol.26 issue3Sociodemographic factors associated with symptoms of depression in a sample of women held at two prisons in MexicoRisk factors for pregnancy among adolescent girls in Ecuador's Amazon basin: a case-control study author indexsubject indexarticles search
Home Page  

Services on Demand




Related links


Revista Panamericana de Salud Pública

On-line version ISSN 1680-5348Print version ISSN 1020-4989


FORTES FILHO, João B. et al. Prevalence of retinopathy of prematurity: an institutional cross-sectional study of preterm infants in Brazil. Rev Panam Salud Publica [online]. 2009, vol.26, n.3, pp.216-220. ISSN 1680-5348.

OBJECTIVE: Retinopathy of prematurity (ROP) is the leading cause of childhood blindness in most developed countries. This study aimed to verify ROP prevalence among all very low birth weight (VLBW) preterm infants admitted to a level-3 teaching hospital in Porto Alegre, Rio Grande do Sul, Brazil. METHODS: Institutional cross-sectional study of 407 premature infants with birth weight <1500 g or gestational age (GA) <32 weeks between 2002 and 2007. All infants screened for ROP were examined after the fourth week of life and followed up until the 45th week of adjusted GA. ROP prevalence was estimated at a 95% confidence level. RESULTS: Some degree of ROP in one or both eyes occurred in 25.5% (104) of all screened infants, and severe ROP (threshold stage 3 or higher, requiring treatment to prevent vision loss, as per the criteria of the U.S.-based Multicenter Trial of Cryotherapy for Retinopathy of Prematurity, CRYO-ROP) occurred in 5.8% (24). Based on the criteria of The International Classification for Retinopathy of Prematurity (ICROP, 1984/1987), the disease reached stages 1, 2, and 3 in 11.3% (46), 8.4% (34), and 5.4% (22), respectively. One infant developed the disease up to stage 4 (partial retinal detachment), and one progressed to stage 5 (complete retinal detachment, resulting in 0.2% overall prevalence for ROP-induced blindness). CONCLUSIONS: Overall incidence of ROP in this institutional study (25.5%) was comparable to international results from developed countries. A comprehensive countrywide survey on ROP in Brazil is recommended to determine any regional differences in disease prevalence.

Keywords : Blindness [prevention & control]; retinopathy of prematurity [epidemiology]; prevalence; Brazil.

        · abstract in Spanish     · text in English     · English ( pdf )