Revista Panamericana de Salud Pública
Print version ISSN 1020-4989
RIVAS, Phenélope and ALONSO, Guillermina. Regulations governing the dispensing of medications and their effect on antibiotic consumption in Venezuela. Rev Panam Salud Publica [online]. 2011, vol.30, n.6, pp. 592-597. ISSN 1020-4989. http://dx.doi.org/10.1590/S1020-49892011001200016.
OBJECTIVE: Determine the variations in consumption trends for regulated and unregulated antibiotics in Venezuela in the period before (2005) and after (2006-2008) the regulation of prescription sales was introduced. METHODS: Information on antibiotic consumption in Venezuela was obtained from the data provided by International Marketing Services. Consumption was expressed in daily doses per 1 000 inhabitants. Analyses of variance (ANOVA) were performed, with a 95% confidence interval, to identify the differences between the periods studied. RESULTS: The regulated antibiotics with the highest consumption were ciprofloxacin and azithromycin. The classes of unregulated antibiotics with the highest consumption were penicillins and first-generation cephalosporins, aminoglycosides, diami-nopyridine-sulfonamides, and tetracyclines. Total consumption in the categories of antibiotics with unregulated dispensing was twice as high as in the categories with regulated sales, both before and after introduction of the regulation. CONCLUSIONS: There were no statistically significant differences in antibiotic consumption with regulated or unregulated dispensing, either before or after the introduction of measures regulating the dispensing of antibiotics.
Keywords : Anti-bacterial agents; drug-resistance, bacterial; legislation, drug; drug utilization; Venezuela.