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Ciência & Saúde Coletiva

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TEIXEIRA, Ilka Nicéia D'Aquino Oliveira  and  GUARIENTO, Maria Elena. Biology of aging: theories, mechanisms, and perspectives. Ciênc. saúde coletiva [online]. 2010, vol.15, n.6, pp.2845-2857. ISSN 1413-8123.

Abstract The article reviews the major biological theories of aging, and discusses the most relevant mechanisms to explain the aging process. It begins with the evolutionary theories, explores the molecular-cellular mechanisms, and presents the perspective of the systemic theories. The complex etiology of aging is a challenge to the researchers. The knowledge on that phenomenon develops towards an integrative approach.

Keywords : Biology; Aging; Cell aging; Cell death; Aged.

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