Revista Peruana de Medicina Experimental y Salud Pública
On-line version ISSN 1726-4642Print version ISSN 1726-4634
GARMENDIA, Fausto; PANDO, Rosa and RONCEROS, Gerardo. Effect of sacha inchi oil (plukenetia volúbilis l) on the lipid profile of patients with hyperlipoproteinemia. Rev Peru Med Exp Salud Publica [online]. 2011, vol.28, n.4, pp.628-632. ISSN 1726-4642. http://dx.doi.org/10.1590/S1726-46342011000400009.
We performed a pilot, experimental, open study in order to know the effect, effective dosage and secondary effects of sacha inchi´s (Plukenetia volúbilis L) oil on the lipid profiles of patients with hypercholesterolemia. We included 24 patients of ages 35 to 75, to whom we measured total cholesterol (TC), HDL, triglycerides (Tg), glucose (G), non-esterified fatty acids (NEFA) and insulin (I) levels in blood, then we randomized them to receive sacha inchi oil orally 5 ml or 10 ml of a suspension of sacha inchi oil (2gr/5ml) for four months. The oil intake produced a decrease in the mean values of TC, and NEFA, and a rise in HDL in both subgroups. The subgroup receiving 10 ml was associated to an increase in the insulin levels. Sacha inchi oil appears to have beneficial effects on the lipid profile of patients with dyslipidemia, but their efficacy and security should be evaluated in randomized clinical trials.
Keywords : Hyperlipoproteinemias; Hypercholesterolemia; Plukenetia volubilis L.