A review of immunization legislation for children in English- and Dutch-speaking Caribbean countries

Revisión de los marcos legislativos sobre vacunación infantil en países de habla inglesa y neerlandesa del Caribe

Revisão da legislação relativa à imunização em crianças nos países do Caribe de língua inglesa e holandesa

Tracy Evans-Gilbert Karen N. Lewis-Bell Beryl Irons Philippe Duclos Gabriel Gonzalez-Escobar Elizabeth Ferdinand J. Peter Figueroa on behalf of the Caribbean Immunization Technical Advisory GroupAbout the authors

ABSTRACT

Objective.

To assess the legislative frameworks concerning childhood vaccination in the English- and Dutch-speaking Caribbean and propose a model legislative framework for Caribbean countries.

Methods.

This study included a survey of 22 countries and territories in the Caribbean regarding legal vaccination mandates for school entry, budget allocations, sanctions, or exemptions. A legal consultant conducted a comprehensive search and analysis of legislation regarding vaccination among 13 Caribbean countries/territories. A comparative analysis of the legislation under five themes—legislative structure, mandatory vaccination, national immunization schedule, sanctions, and exemptions—formed the basis for the proposed model legislation.

Results.

Among the 22 Caribbean countries/territories, 17 (77%) had legislation mandating vaccination, 16 (94%) mandated vaccination for school entry, 8 (47%) had a dedicated budget for immunization programs, and 13 (76%) had no legislated national schedules. The source of legislation includes six (35%) using the Education Act, eight (47%) the Public Health Act, and five (29%) a free-standing Vaccination Act. Three countries/territories—Jamaica, Montserrat, and Saint Lucia—had immunization regulations. In 12 (71%) of the 17 countries with legislation, sanctions were included, and 10 (59%) permitted exemptions for medical or religious/philosophical beliefs.

Conclusions.

Several countries in the Caribbean have made failure to vaccinate a child an offense. By summarizing the existing legislative frameworks and approaches to immunization in the Caribbean, the analysis guides policymakers in making effective changes to immunization legislation in their own countries.

Keywords
Immunization; legislation; evidence-informed policy; decision making; health policy; pediatrics; Caribbean region

RESUMEN

Objetivo.

Evaluar los marcos legislativos relativos a la vacunación infantil en el Caribe de habla inglesa y neerlandesa y proponer un modelo de marco legislativo para los países del Caribe.

Métodos.

En este estudio se incluyó una encuesta en 22 países y territorios del Caribe sobre los requisitos legales de vacunación para el ingreso escolar, asignaciones presupuestarias, sanciones o exenciones. Un consultor jurídico realizó una búsqueda y un análisis exhaustivos de la legislación relativa a la vacunación en 13 países y territorios del Caribe. Un análisis comparativo de la legislación dividido en cinco temas (estructura legislativa, vacunación obligatoria, calendario nacional de vacunación, sanciones y exenciones) formó la base del modelo de legislación propuesto.

Resultados.

Entre los 22 países y territorios del Caribe, 17 (77%) contaban con leyes sobre vacunación obligatoria, 16 (94%) exigían la vacunación para el ingreso escolar, 8 (47%) tenían un presupuesto dedicado a los programas de vacunación y 13 (76%) no disponían de calendarios nacionales estipulados por ley. Entre las fuentes de la legislación, seis países y territorios (35%) empleaban la ley de educación, ocho (47%) la ley de salud pública y cinco (29%) una ley independiente de vacunación. Tres países y territorios —Jamaica, Montserrat y Santa Lucía— disponían de regulaciones sobre vacunación. Doce (71%) de los 17 países con legislación tenían sanciones y 10 (59%) permitían exenciones por creencias médicas o religiosas o filosóficas.

Conclusiones.

Varios países del Caribe han tipificado como delito el no vacunar a un niño o niña. Al resumir los enfoques y marcos legislativos existentes para la vacunación en el Caribe, este análisis ofrece orientaciones a los responsables de formular las políticas para que realicen modificaciones efectivas en la legislación relativa a la vacunación en sus propios países.

Palabras clave
Inmunización; legislación; política informada por la evidencia; toma de decisiones; política de salud; pediatría; región del Caribe

RESUMO

Objetivo.

Avaliar as estruturas da legislação relativas à vacinação em crianças no Caribe de língua inglesa e holandesa e propor um modelo de legislação para os países caribenhos.

Métodos.

Este estudo incluiu uma pesquisa relativa à exigência legal em 22 países e territórios do Caribe de vacinação para admissão em escolas, alocações orçamentárias, sanções ou isenções. Um consultor jurídico realizou ampla pesquisa e análise da legislação relativa à vacinação em 13 países/territórios do Caribe. Uma análise comparativa da legislação referente a cinco temas – estrutura legislativa, vacinação obrigatória, cronograma nacional de imunização, sanções e isenções – formou a base para o modelo de legislação proposto.

Resultados.

Entre os 22 países/territórios caribenhos, 17 (77%) tinham legislação que exigia a vacinação; em 16 (94%), a vacinação era obrigatória para admissão na escola; 8 (47%) tinham orçamento exclusivo para programas de imunização; e em 13 (76%), a legislação não contemplava cronogramas nacionais. Com relação à fonte da legislação, seis (35%) países usavam a legislação de educação; oito, (47%) a Legislação de Saúde Pública; e cinco (29%), legislação de vacinação independente. Três países/territórios - Jamaica, Montserrat e Santa Lúcia - tinham regulamentações para imunização. Dos 17 países com legislação, 12 (71%) incluíam sanções e 10 (59%) permitiam isenções por crenças médicas ou religiosas/filosóficas.

Conclusões.

Diversos países do Caribe estabelecem que não vacinar uma criança é violação da lei. Ao resumir as estruturas de legislação existentes e as abordagens da imunização no Caribe, a análise orienta os formuladores de políticas a realizar mudanças efetivas na legislação de imunização em seus próprios países.

Palavras-chave
Imunização; legislação; política informada por evidências; tomada de decisões; política de saúde; pediatria; região do Caribe

Mandatory pediatric immunization is relatively common globally (11. Harmon SHE, Faour DE, MacDonald NE, Graham JE, Steffen C, Henaff L, et al. Immunization governance: Mandatory immunization in 28 Global NITAG Network countries. Vaccine. 2020;38(46):7258–67. https://doi.org/10.1016/j.vaccine.2020.09.053
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, 22. Gravagna K, Becker A, Valeris-Chacin R, Mohammed I, Tambe S, Awan FA, et al. Global assessment of national mandatory vaccination policies and consequences of non-compliance. Vaccine. 2020;38(49):7865–73. https://doi.org/10.1016/j.vaccine.2020.09.063
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) and varies with the immunizations required, population groups, grounds for exemptions, and penalties for non-compliance (11. Harmon SHE, Faour DE, MacDonald NE, Graham JE, Steffen C, Henaff L, et al. Immunization governance: Mandatory immunization in 28 Global NITAG Network countries. Vaccine. 2020;38(46):7258–67. https://doi.org/10.1016/j.vaccine.2020.09.053
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33. Vanderslott S, Marks T. Charting mandatory childhood vaccination policies worldwide. Vaccine. 2021;39(30):4054–62. https://doi.org/10.1016/j.vaccine.2021.04.065
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). The most common mandates of national immunization programs are related to school entry for children to protect against childhood diseases. Among Global NITAG (National Immunization Technical Advisory Group) Network (GNN) countries, mandatory vaccine policies are found mainly among high-income and upper-middle-income countries compared with lower-middle-income and low-income countries. Moreover, they are most prevalent in the Americas compared with other World Health Organization (WHO) regions (11. Harmon SHE, Faour DE, MacDonald NE, Graham JE, Steffen C, Henaff L, et al. Immunization governance: Mandatory immunization in 28 Global NITAG Network countries. Vaccine. 2020;38(46):7258–67. https://doi.org/10.1016/j.vaccine.2020.09.053
https://doi.org/10.1016/j.vaccine.2020.0...
). In Latin America and the Caribbean, commencing in the 1980s and 1990s, public health laws played a role in successful national immunization programs in the region, contributing to polio and other disease eradication campaigns, but varied in their legal framework (44. Trumbo SP, Janusz CB, Jauregui B, McQuestion M, Felix G, Ruiz-Matus C, et al. Vaccination legislation in Latin America and the Caribbean. J Public Health Policy. 2013;34(1):82–99. https://doi.org/10.1057/jphp.2012.66
https://doi.org/10.1057/jphp.2012.66...
).

Historically, legislation and policies governing immunization in countries such as Australia, the United Kingdom, and the United States of America have contributed to achieving and sustaining high vaccination coverage rates and have greatly reduced disease outbreaks among school-aged children (55. Salmon DA, Teret SP, MacIntyre CR, Salisbury D, Burgess MA, Halsey NA. Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future. Lancet. 2006;367(9508):436–42. https://doi.org/10.1016/S0140-6736(06)68144-0
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66. Omer SB, Betsch C, Leask J. Mandate vaccination with care. Nature. 2019;571(7766):469–72. https://doi.org/10.1038/d41586-019-02232-0
https://doi.org/10.1038/d41586-019-02232...
). Policies or legislation governing school entry requirements, complex administrative procedures required to obtain exemptions, and penalties have proved to be effective methods for improving vaccination coverage rates (66. Omer SB, Betsch C, Leask J. Mandate vaccination with care. Nature. 2019;571(7766):469–72. https://doi.org/10.1038/d41586-019-02232-0
https://doi.org/10.1038/d41586-019-02232...
).

The English- and Dutch-speaking Caribbean successfully eliminated polio in 1982, measles in 1991, diphtheria in 1994, congenital rubella syndrome in 1999, neonatal tetanus in 2000, and rubella in 2001 (77. Lewis-Bell KN, Irons B, Ferdinand E, Jackson LL, Figueroa JP. The Expanded Program on Immunization in the English- and Dutch-speaking Caribbean (1977–2016): reasons for its success. Rev Panam Salud Publica. 2017;41:e127. https://doi.org/10.26633/RPSP.2017.127
https://doi.org/10.26633/RPSP.2017.127...
). These achievements followed the establishment of the Expanded Program on Immunization (EPI) in 1977 and measures to strengthen the institutional structures of immunization and surveillance programs at national and regional levels as well as systematic activities and campaigns to eliminate these diseases. The Revolving Fund of the Pan American Health Organization (PAHO) ensured a ready supply of vaccines at reasonable cost. Countries took ownership of their EPI programs and provided 95% or more of their financing, with only Guyana receiving support from GAVI, The Vaccine Alliance. For sustainability, countries were encouraged to secure a budget line for the EPI program and national vaccine supplies. Vaccine laws provided a legal framework to ensure a specific budget allocation for vaccine purchases in Latin American and Caribbean countries (44. Trumbo SP, Janusz CB, Jauregui B, McQuestion M, Felix G, Ruiz-Matus C, et al. Vaccination legislation in Latin America and the Caribbean. J Public Health Policy. 2013;34(1):82–99. https://doi.org/10.1057/jphp.2012.66
https://doi.org/10.1057/jphp.2012.66...
, 77. Lewis-Bell KN, Irons B, Ferdinand E, Jackson LL, Figueroa JP. The Expanded Program on Immunization in the English- and Dutch-speaking Caribbean (1977–2016): reasons for its success. Rev Panam Salud Publica. 2017;41:e127. https://doi.org/10.26633/RPSP.2017.127
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, 88. Tambini G, Andrus JK, Fitzsimmons JW, Roses Periago M. Regional immunization programs as a model for strengthening cooperation among nations. Rev Panam Salud Publica. 2006;20(1):54–9. https://doi.org/10.1590/s1020-49892006000700012
https://doi.org/10.1590/s1020-4989200600...
). The expansion of legal frameworks concerning vaccination accompanied improvement in national immunization program performance and national immunization financing (44. Trumbo SP, Janusz CB, Jauregui B, McQuestion M, Felix G, Ruiz-Matus C, et al. Vaccination legislation in Latin America and the Caribbean. J Public Health Policy. 2013;34(1):82–99. https://doi.org/10.1057/jphp.2012.66
https://doi.org/10.1057/jphp.2012.66...
). Through legislation in public health and education, 80% of countries in the subregion have mandatory vaccination requirements for school entry (99. Pan American Health Organization. Thirty-first Meeting of the Caribbean Immunization Managers, Final Report, Georgetown, Guyana 17–19 November 2015. Washington, DC: PAHO; 2016. Available from: https://www.paho.org/en/node/56334
https://www.paho.org/en/node/56334...
).

Traditionally high immunization coverage in the Caribbean has declined from 2015–2020, with many districts reporting coverage of childhood vaccines below 80%. The decline in immunization coverage has been exacerbated by the COVID-19 pandemic. Additionally, a decline in the surveillance of suspected measles, rubella, and polio cases occurred in the Caribbean in 2020 (1010. Pan American Health Organization. Thirty-fifth Meeting of Managers of the Caribbean Expanded Program on Immunization, Final Report, Virtual Meeting, 3–5 November 2021. Washington, DC: PAHO; 2022. Available from: https://www.paho.org/en/node/86032
https://www.paho.org/en/node/86032...
). Vaccine misinformation, manipulated information, and conflicting information promoted on digital platforms during the COVID-19 pandemic potentially reduced confidence in vaccines. Prior to the COVID-19 pandemic, a social movement opposing public health vaccinations resulted in the increased allowance of nonmedical exemptions (NMEs) and the re-emergence of vaccine-preventable diseases (VPD) (1111. Ernst KC, Jacobs ET. Implications of philosophical and personal belief exemptions on re-emergence of vaccine-preventable disease: the role of spatial clustering in under-vaccination. Hum Vaccin Immunother. 2012;8(6):838–41. https://doi.org/10.4161/hv.19743
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). This changing view regarding vaccination threatens to erode existing public health achievements toward VPD elimination.

The influx of tourists (1212. Caribbean Tourism Organization [Internet]. St Michael, Barbados: CTO; c2022 [cited 2022 Oct 2]. Annual Reviews and Prospects 2019. Available from: https://www.onecaribbean.org/statistics/annual-reviews-prospects/.
https://www.onecaribbean.org/statistics/...
) far exceeds the combined population of 7 million persons in the English- and Dutch-speaking Caribbean (1313. International Federation of Red Cross and Red Crescent Societies. Dutch and English Speaking Caribbean Countries IFRC Country Cluster [Internet]. [Trinidad and Tobago]: IFRC; 2021 [cited 2022 Oct 10]. Available from: https://www.ifrc.org/sites/default/files/2021-08/Dutch_English_speaking_Caribbean_Plan_2021.pdf
https://www.ifrc.org/sites/default/files...
). Considering the emerging public health threat of the reintroduction of VPDs in the Caribbean and the global public health crisis of under-immunization of children, an urgent review of current vaccine policies and legislation is necessary. It should accompany other strategies to ensure accessibility to vaccines and interventions to improve uptake of vaccines and reduce disease outbreaks (66. Omer SB, Betsch C, Leask J. Mandate vaccination with care. Nature. 2019;571(7766):469–72. https://doi.org/10.1038/d41586-019-02232-0
https://doi.org/10.1038/d41586-019-02232...
). Mass communication campaigns integral to the success of measles and rubella elimination, lessons learned, and best practices should be reinforced (1414. Castillo-Solorzano C, Marsigli C, Danovaro-Holliday MC, Ruiz- Matus C, Tambini G, Andrus JK. Measles and Rubella Elimination Initiatives in the Americas: Lessons Learned and Best Practices. J Infect Dis. 2011;204(suppl_1):279–83. https://doi.org/10.1093/infdis/jir216
https://doi.org/10.1093/infdis/jir216...
).

This review aligns with one of the objectives of the second strategic priority of the Immunization Agenda 2030 (IA 2030), to build and sustain a strong political and financial commitment to immunization at all levels (1515. World Health Organization [Internet]. Geneva: WHO; c2021 [cited 2022 Oct 10]. Immunization Agenda 2030: A Global Strategy to Leave No One Behind. Available from: https://www.who.int/teams/immunization-vaccines-and-biologicals/strategies/ia2030
https://www.who.int/teams/immunization-v...
). It also aims to assess the legislative frameworks concerning childhood vaccination in the English- and Dutch-speaking Caribbean and propose a model legislative framework for Caribbean countries.

MATERIALS AND METHODS

This was a descriptive study of the legislation and regulations concerning vaccination in children among English- and Dutch-speaking countries and territories in the Caribbean, which include Anguilla, Antigua and Barbuda, Aruba, The Bahamas, Barbados, Belize, Bermuda, British Virgin Islands, Cayman Islands, Curaçao, Dominica, Grenada, Guyana, Jamaica, Montserrat, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Sint Maarten, Suriname, Trinidad and Tobago, and Turks and Caicos Islands.

An Act of Parliament is defined as a law or statute passed by the Parliament after debate in both Houses. Under the Act, a regulation is passed that details how an Act should be implemented, and this is also known as “subsidiary legislation.” Acts such as the Public Health Act, Vaccination Act, and Education Act give the general framework from which health regulations concerning vaccination are drafted. Policies are statements of intent that guide government decisions and actions in what it can achieve for society. Policies are documents not laws, but can lead to the formation of new laws. Vaccination policies that were not laws or regulations were not reviewed.

The study was conducted in two phases. During the first phase, an online survey was conducted among EPI managers of 22 English- and Dutch-speaking countries and territories in the Caribbean. The survey, distributed by email, consisted of a structured questionnaire on five broad themes: the presence of legislation mandating vaccination, legal vaccination mandates for school entry, and the presence or absence of sanctions, exemptions, and a dedicated budget line for EPI. In addition, there were open-ended questions on the year of legislation, source of legislation, and the description of sanctions if present. To minimize nonresponse, the survey was kept short and emailed reminders were sent. The information was summarized and tabulated.

During the second phase, a legal consultant conducted a comprehensive search and analysis of all laws and regulations regarding vaccination among the 13 countries and territories. A comparative study of the frameworks applied in each country/territory was conducted by the research team, which was comprised of the authors and two legal consultants. The analysis was categorized according to five domains: legislative structure, mandatory vaccination, presence of a national immunization schedule, exemptions, and sanctions.

A model legislative framework was then derived from these analyses and a review of the literature.

RESULTS

Among the 22 English- and Dutch-speaking Caribbean countries and territories examined, 17 (77%) had currently active legislation mandating vaccination. Table 1 provides a background of immunization legislation in the Caribbean against the timeline of the EPI program and VPD elimination. Seven countries enacted immunization laws prior to the formation of the EPI in 1977, four between 1986 and 1998 and six from 2004 to 2013. Figure 1 shows diphtheria–tetanus–pertussis third dose (DTP3) coverage between 1980 and 2007 in five Caribbean countries with legislation between 1978 and 1998. The figure suggests an increase in vaccination coverage in all five countries following vaccination legislation and institutionalization of vaccination activities. In Belize, the Public Health Act was instituted in 1946 and DTP3 coverage was below 50% in 1980. After the EPI and other regional immunization activities were instituted, coverage rates increased to 82%–89% for about a decade. The Family and Children’s Act was passed with the adoption of the Convention on the Rights of the Child in 1998, followed by a revision of the Public Health Act in 1999. Immunization coverage rates increased to greater than 95% from 2001 to 2007, peaking at 98% in 2006. In Saint Lucia, immunization coverage rates were 27% in 1980, increased to 89% in 1987 and to 95%–99% between 1989 and 2005. Regulations under the Public Health Act in 1991 stipulated a legal requirement for vaccination prior to school entry. Table 2 summarizes countries with existing legislation. The five countries and territories without legislation were Aruba, Cayman Islands, Curaçao, Sint Maarten, and Turks and Caicos Islands. Most English-speaking Caribbean countries have not revised their legislation governing immunization. Barbados, Belize, Jamaica, Saint Lucia, and Saint Vincent and the Grenadines have amended their immunization legislation in 2018, 2010, 2013, 1991, and 2009, respectively (Table 1 and 2). Most countries (16, 94%) mandated vaccination for school entry. The source of legislation varied, with six (35%) using the Education Act, eight (47%) the Public Health Act, and five (29%) a free-standing Vaccination Act. Three countries and territories—Jamaica, Montserrat, and Saint Lucia—had immunization regulations under the Public Health Act. In 12 (71%) of the 17 countries with legislation, sanctions were included, and 10 (59%) permitted exemptions for medical or religious/philosophical beliefs. Among the countries with an existing legislative framework, 8 (47%) included a dedicated budget for the EPI.

FIGURE 1.
DTP3 coverage by year in five Caribbean countries with legislation between 1978 and 1998*

A comparative analysis of the legislation is summarized in Table 3. The legislative frameworks varied among countries. Legislative structures without an Act of Parliament specifically dealing with vaccination tend to have regulations under their Public Health or Education Acts. All vaccination legislation in the countries reviewed, whether expressed or implied, provide the right for every parent or person having custody of a child to vaccinate the child. The time frame to commence vaccination varied, ranging from no age stipulation to before 3, 6, or 12 months.

While some acts and regulations, such as the Immunization of Children Act for Saint Vincent and the Grenadines and the Public Health Regulations (Communicable and Notifiable Disease) of Saint Lucia, are silent on the specific time frame that vaccination should be done, most legislations provide a requirement that the vaccination should be done before registering a child in a school. Vaccination as a public good was not explicitly stated. However, most countries provide vaccinations for free as a public good.

A national vaccination schedule was not stipulated in 13 (76%) countries or was limited in coverage among the schedules that were included. Newer vaccines such as pneumococcal or human papillomavirus (HPV) vaccines were not mentioned. Historically, all countries and territories were conducting routine immunization with the DTP, polio, measles, and bacillus Calmette–Guérin (BCG) vaccines in 1980 (1616. Pan American Health Organization, Epidemiology/EPI Unit; Caribbean Epidemiology Centre. A historical review of the Expanded Program on Immunization in the English-speaking Caribbean and Suriname, 1977–1993. Port of Spain: PAHO/WHO/CAREC; 1994.). In 2002–2006, all countries/territories in the subregion introduced the childhood vaccines for hepatitis B and Haemophilus influenzae type b as well as the routine second dose of the measles, mumps, and rubella (MMR) vaccine (MMR2) (77. Lewis-Bell KN, Irons B, Ferdinand E, Jackson LL, Figueroa JP. The Expanded Program on Immunization in the English- and Dutch-speaking Caribbean (1977–2016): reasons for its success. Rev Panam Salud Publica. 2017;41:e127. https://doi.org/10.26633/RPSP.2017.127
https://doi.org/10.26633/RPSP.2017.127...
). Certificates for medical exemptions included different times for renewal ranging from 2 to 3 months. Among countries with sanctions, the fees were outdated and insufficient to be considered useful deterrents with few exceptions. The fines ranged from the equivalent of US$ 0.09–92 in Belize, Bahamas, Dominica, Grenada, Montserrat, and Saint Lucia, whereas Jamaica imposed a penalty of J$ 1 million, equivalent to approximately US$ 6 500. Sanctions in most legislation focused on the parents of unvaccinated children, while legislation such as the Immunization of Children Act for Saint Vincent and the Grenadines is comprehensive in its approach. It incorporates parents, persons who willfully sign false certificates, and health officers or medical practitioners who knowingly administer expired vaccines.

TABLE 1.
Timeline of the Expanded Program on Immunization, vaccine-preventable disease elimination, and immunization legislation by Caribbean country/territory

DISCUSSION

In the Caribbean, immunization legislation was enacted before, during, and after the establishment of the EPI in the region. Most countries and territories have adopted legislation requiring vaccination, with a mandate for school entry, and these varied within the legal framework. The five countries and territories without legislation are Aruba, Cayman Islands, Curaçao, Sint Maarten, and Turks and Caicos, which are dependent territories subject to legislation of either the United Kingdom or the Netherlands. Some United Kingdom Overseas Territories such as the British Virgin Islands, Montserrat, and Bermuda have vaccination legislation. Four countries made amendments to their legislation. The time frame for immunization varied, most did not have a stipulated national vaccination schedule, exemptions varied, sanctions were not sufficient deterrents, and fiscal support did not always complement legislative efforts. The differences in legislation may impact vaccination coverage. In the United States of America, interstate variations in immunization laws impacted vaccination coverage and exemption rates. State laws allowing both religious and philosophical exemptions and laws permitting scalable exemptions were associated with decreased MMR and DTaP coverage rates. State laws associated with policy referral to Advisory Committee on Immunization Practices guidelines for school entry had higher vaccination coverage and lower nonmedical exemption rates for MMR and DTaP vaccines (1717. Shaw J, Mader EM, Bennett BE, Vernyi-Kellogg OK, Yang YT, Morley CP. Immunization Mandates, Vaccination Coverage, and Exemption Rates in the United States. Open Forum Infect Dis. 2018 Jun 2;5(6):ofy130. https://doi.org/10.1093/ofid/ofy130
https://doi.org/10.1093/ofid/ofy130...
). In the Caribbean, reintroduction of a VPD in any island could spread easily in the region due to brisk travel among the countries, and vulnerabilities due to low coverage and surveillance (1010. Pan American Health Organization. Thirty-fifth Meeting of Managers of the Caribbean Expanded Program on Immunization, Final Report, Virtual Meeting, 3–5 November 2021. Washington, DC: PAHO; 2022. Available from: https://www.paho.org/en/node/86032
https://www.paho.org/en/node/86032...
).

TABLE 2.
Legislation and regulations in 22 Caribbean countries and territories

Countries that do not have an Act of Parliament or law specifically dealing with vaccination tend to address this issue with regulations under their Public Health Act or in their Educational Legislation. The best measure to be adopted according to legal experts is to pass a law or Act of Parliament and develop regulations under this law to assist with the implementation of the provisions of the Act. The regulations in Jamaica are extensive, but these are only regulations and are thus subject to easy removal and rewriting. An Act of Parliament is much more secure and durable.

Ideally, there should be a comprehensive legal statement of the rights of citizens to health care and detailed legislation or Act(s) of Parliament to make those guarantees real in practice. Generally, Commonwealth English-speaking Caribbean States have constitutional provisions that state the fundamental rights and freedoms of individuals in each jurisdiction. However, only Guyana states the right to health care in its constitution. Changes in the constitution require cooperation among political parties or a public referendum. Historically, to pass a vaccination law successfully, there is need for cooperation among parliamentarians, government officials, multiple disciplines, opposing political parties, and several levels of national authority (44. Trumbo SP, Janusz CB, Jauregui B, McQuestion M, Felix G, Ruiz-Matus C, et al. Vaccination legislation in Latin America and the Caribbean. J Public Health Policy. 2013;34(1):82–99. https://doi.org/10.1057/jphp.2012.66
https://doi.org/10.1057/jphp.2012.66...
).

The duty to immunize is universal. For example, the first statement of the Immunization Act in Jamaica declares, “It is the duty of every parent to have their child immunized.” However, policies regarding school entry requirements do not generally apply to children younger than school age or explicitly ensure the vaccination of home-schooled children.

Among those reviewed from Caribbean countries, not all made allowances for medical exemptions, and few permitted exemptions based on religious or philosophical reasons, which increase the opportunities for vaccine refusal (Table 2). The allowance of NMEs introduces the risk of increasing the vulnerable, unimmunized children.

Mature vaccination programs in Australia and the United States of America that successfully utilized vaccination legislation to achieve high vaccination coverage rates and eliminate or reduce VPDs saw re-emergence in VPDs commensurate with increase in NMEs. The increased NME rates in 12 of 18 states in the United States of America were inversely associated with the measles, mumps, and rubella coverage rates among preschool-aged children (1818. Robbins KB, Brandling-Bennett D, Hinman AR. Low measles incidence: association with enforcement of school immunization laws. Am J Public Health. 1981;71(3):270–4. https://doi.org/10.2105/ajph.71.3.270
https://doi.org/10.2105/ajph.71.3.270...
). Government policies removing NMEs were effective at increasing vaccination coverage. In 2016, a California policy eliminated NMEs from school entry requirements, which resulted in substantial increases in vaccination coverage in 2017 compared with 2015, particularly for counties with the lowest pre-policy coverage rates (1919. Nyathi S, Karpel HC, Sainani KL, Maldonado Y, Hotez PJ, Bendavid E, et al. The 2016 California policy to eliminate nonmedical vaccine exemptions and changes in vaccine coverage: An empirical policy analysis. PLoS Med. 2019;16(12):e1002994. https://doi.org/10.1371/journal.pmed.1002994
https://doi.org/10.1371/journal.pmed.100...
). These legislative and policy changes should complement efforts to examine parental perceptions about vaccination and effectively communicate information regarding the risks and benefits of vaccines. Countries and territories that permit medical exemptions with variable durations support the importance of stipulating the time to renewal in the legislation.

Most countries outlined compulsory vaccines, but there was a lack of stringent enforcement measures to deter offenders. The modest fines quoted in most countries render the legislation ineffective. In The Bahamas, the penalty for a caregiver who fails to vaccinate their child is US$ 4. Few countries included criminal penalties for non-compliance ranging from 3 to 12 months of imprisonment, which may serve as deterrent, but enforcement was not confirmed. In 2017, vaccination against childhood VPDs became compulsory in Italy. This law imposed substantial monetary fines on the families of unvaccinated children when they attempted to attend primary school (2020. Signorelli C, Iannazzo S, Odone A. The imperative of vaccination put into practice. Lancet Infect Dis. 2018;18(1):26–7. https://doi.org/10.1016/S1473-3099(17)30696-5
https://doi.org/10.1016/S1473-3099(17)30...
). Vaccine coverage had increased for all vaccines by 0.7%–5.2% one year later (2121. D'Ancona F, D'Amario C, Maraglino F, Rezza G, Iannazzo S. The law on compulsory vaccination in Italy: an update 2 years after the introduction. Euro Surveill. 2019;24(26):1900371. https://doi.org/10.2807/1560-7917.ES.2019.24.26.1900371
https://doi.org/10.2807/1560-7917.ES.201...
). Sanctions may not be necessary if public demand for vaccinations exists. Engendering a trust relationship through training of health professionals, increasing vaccine-related knowledge among providers and the public, and ensuring availability and safety of vaccines should complement legislative actions. Mandatory vaccination policies should not deprive children of the opportunity to attend school. The second strategic priority of the IA 2030 agenda encourages the engendering of public trust in vaccination in addition to political commitment (1515. World Health Organization [Internet]. Geneva: WHO; c2021 [cited 2022 Oct 10]. Immunization Agenda 2030: A Global Strategy to Leave No One Behind. Available from: https://www.who.int/teams/immunization-vaccines-and-biologicals/strategies/ia2030
https://www.who.int/teams/immunization-v...
). In the Caribbean, the importance given to education by parents helps to motivate them to have their children vaccinated, since it is a requirement for school entry. Sanctions in most legislation focused on penalties to parents of unvaccinated children and delinquent medical practitioners. The use of sanctions to enhance vaccine coverage is not helpful if sanctions are not implemented.

There were seven countries that implemented legislation prior to the EPI in 1977 (Table 1) and vaccine coverage was suboptimal. Immunization legislation by itself does not address vaccine hesitancy (2222. Ludvigsson JF, Loboda A. Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees. Acta Paediatr. 2022;111(7):1341–53. https://doi.org/10.1111/apa.16370
https://doi.org/10.1111/apa.16370...
) or unstructured vaccine elimination strategies. Limited analysis suggests that legislation may have contributed to sustained and increased immunization coverage rates (Figure 1), and this is supported in mature immunization programs with legislation (33. Vanderslott S, Marks T. Charting mandatory childhood vaccination policies worldwide. Vaccine. 2021;39(30):4054–62. https://doi.org/10.1016/j.vaccine.2021.04.065
https://doi.org/10.1016/j.vaccine.2021.0...
, 55. Salmon DA, Teret SP, MacIntyre CR, Salisbury D, Burgess MA, Halsey NA. Compulsory vaccination and conscientious or philosophical exemptions: past, present, and future. Lancet. 2006;367(9508):436–42. https://doi.org/10.1016/S0140-6736(06)68144-0
https://doi.org/10.1016/S0140-6736(06)68...
, 66. Omer SB, Betsch C, Leask J. Mandate vaccination with care. Nature. 2019;571(7766):469–72. https://doi.org/10.1038/d41586-019-02232-0
https://doi.org/10.1038/d41586-019-02232...
).

Most countries’ EPI legislations do not include the right to vaccination as a public good or the responsibility of the government to ensure sustained vaccines and supplies through a dedicated budget line for immunization. The enactment of legislation without government commitment and the necessary budget to implement and sustain vaccination programs is ineffective. Effective vaccine programs in Australia and the United States of America that are associated with compulsory vaccination models included a reliable supply of safe and effective vaccines (66. Omer SB, Betsch C, Leask J. Mandate vaccination with care. Nature. 2019;571(7766):469–72. https://doi.org/10.1038/d41586-019-02232-0
https://doi.org/10.1038/d41586-019-02232...
).

Countries such as France and Ukraine have mandatory vaccination programs, including robust monitoring and follow-up; however, both countries experienced large measles outbreaks. In these countries, vaccine hesitancy is common and contributes to low vaccination rates among children (2222. Ludvigsson JF, Loboda A. Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees. Acta Paediatr. 2022;111(7):1341–53. https://doi.org/10.1111/apa.16370
https://doi.org/10.1111/apa.16370...
2323. Hadjipanayis A, van Esso D, Del Torso S, Dornbusch HJ, Michailidou K, Minicuci N, et al. Vaccine confidence among parents: Large scale study in eighteen European countries. Vaccine. 2020 Feb 5;38(6):1505–12. https://doi.org/10.1016/j.vaccine.2019.11.068
https://doi.org/10.1016/j.vaccine.2019.1...
). Maintaining high homogeneous vaccination coverage across all districts, combined with intense surveillance and rapid outbreak response appear to be essential as well as addressing vaccine hesitancy complemented by legislation and policies (33. Vanderslott S, Marks T. Charting mandatory childhood vaccination policies worldwide. Vaccine. 2021;39(30):4054–62. https://doi.org/10.1016/j.vaccine.2021.04.065
https://doi.org/10.1016/j.vaccine.2021.0...
, 2222. Ludvigsson JF, Loboda A. Systematic review of health and disease in Ukrainian children highlights poor child health and challenges for those treating refugees. Acta Paediatr. 2022;111(7):1341–53. https://doi.org/10.1111/apa.16370
https://doi.org/10.1111/apa.16370...
, 2424. Lévy-Bruhl D, Desenclos JC, Quelet S, Bourdillon F. Extension of French vaccination mandates: from the recommendation of the Steering Committee of the Citizen Consultation on Vaccination to the law. Euro Surveill. 2018 Apr;23(17):18-00048. https://doi.org/10.2807/1560-7917.es.2018.23.17.18-00048
https://doi.org/10.2807/1560-7917.es.201...
, 2525. Eskola J, Duclos P, Schuster M, MacDonald NE; SAGE Working Group on Vaccine Hesitancy. How to deal with vaccine hesitancy? Vaccine. 2015 Aug 14;33(34):4215–7. https://doi.org/10.1016/j.vaccine.2015.04.043
https://doi.org/10.1016/j.vaccine.2015.0...
).

TABLE 3.
Comparative analysis of legislation and proposed themes of model vaccine-related legislation for the Caribbean

The political frameworks and legal and health systems are generally similar among the English-speaking countries, but the economic ability and performance of governments do vary (2626. Martínez R (ed.). Institutional frameworks for social policy in Latin America and the Caribbean [Internet]. ECLAC Books, No. 146 (LC/PUB.2017/14-P/Rev.1). Santiago: Economic Commission for Latin America and the Caribbean (ECLAC); 2019 [cited 2021 Oct 10]. Available from: https://repositorio.cepal.org/bitstream/handle/11362/44170/7/S1900423_en.pdf
https://repositorio.cepal.org/bitstream/...
). All countries have the capacity to support vaccination programs. The model that some but not all Caribbean countries/territories have adopted obligates the government to provide and finance vaccination and to mandate vaccination for school entry. This study identified areas where governments could update their vaccination policy and legislation in ways that could strengthen their immunization programs.

The outputs of this study are similar to the mandatory immunization legislation in other GNN countries with diversity in the number of childhood vaccines mandated, universal exemptions from mandates for medical purposes, and rare NMEs. Sanctions for failure to immunize varied, ranging from no penalty to loss of access to social services (particularly school admission), monetary fines, and incarceration (1010. Pan American Health Organization. Thirty-fifth Meeting of Managers of the Caribbean Expanded Program on Immunization, Final Report, Virtual Meeting, 3–5 November 2021. Washington, DC: PAHO; 2022. Available from: https://www.paho.org/en/node/86032
https://www.paho.org/en/node/86032...
). Further, there appears to be some variance between countries regarding how strictly immunization mandates are enforced, but this was not assessed in this study.

The study was limited with regard to the assessment of legislative implementation and compliance, the monitoring of legal requirements, the impact of sanctions and exemptions on vaccination, and legislation enacted in parent countries of Dutch- and English-speaking dependent territories. The review did not assess the implementation of regulatory oversight to ensure safe and efficacious vaccines. Although the initiation of legislation was contextualized with the EPI timeline in Table 1 and DTP3 dose in Figure 1, a detailed analysis of the impact on vaccination coverage and VPD incidence rates was beyond the scope of this review. Stipulated national vaccine schedules were identified, but a detailed analysis of schedules was not undertaken. Despite these limitations in summarizing the existing legislative frameworks and approaches to immunization in the Caribbean, the analysis provides guidance to policymakers in making effective changes to immunization legislation in their own countries.

The model legislation (Table 3) adapted components of best practices outlined in a previous review of legislation in Latin American and Caribbean countries (44. Trumbo SP, Janusz CB, Jauregui B, McQuestion M, Felix G, Ruiz-Matus C, et al. Vaccination legislation in Latin America and the Caribbean. J Public Health Policy. 2013;34(1):82–99. https://doi.org/10.1057/jphp.2012.66
https://doi.org/10.1057/jphp.2012.66...
). This included specifying target groups for school entry and establishing vaccination as a free public good. Other factors such as exemptions and sanctions were suggested for shaping mandatory national immunization programs among GNN countries (11. Harmon SHE, Faour DE, MacDonald NE, Graham JE, Steffen C, Henaff L, et al. Immunization governance: Mandatory immunization in 28 Global NITAG Network countries. Vaccine. 2020;38(46):7258–67. https://doi.org/10.1016/j.vaccine.2020.09.053
https://doi.org/10.1016/j.vaccine.2020.0...
). Bills for Parliament are written by each government’s drafting department. Although model legislation and legislation from other countries are considered, the end product is unique to each country and will reflect its values. Thus, the model legislation presented here can only suggest the provisions that should be considered. The exact wording can only be the government’s words through its legal drafters.

In conclusion, we recommend a regulatory model that includes the following points. Vaccination should be declared a public good with the responsibility of governments to ensure ready access to essential childhood vaccines and other important vaccines across the life course. Every parent or guardian is responsible for having each child fully vaccinated according to its national schedule and prior to school entry or attendance at a daycare. Exemptions from vaccination should be limited to medical reasons only.

Mandatory childhood vaccination is an important policy intervention for governments trying to address low vaccination rates. Legislation should complement, not replace, other strategies to achieve and sustain high rates of vaccination. Unified legislative approach should be supported by government commitments to vaccine programs and complementary public health measures to improve vaccination coverage and engender vaccine confidence.

Disclaimer.

The authors bear sole responsibility for the views expressed in the manuscript, which may not necessarily reflect the opinions or policies of the RPSP/PAJPH and/or PAHO.

Acknowledgments.

We would like to thank Attorneys-at-Law Nancy Anderson and Michelle Thomas for the review of the legislation. Members of the Caribbean Immunization Technical Advisory Group include Professor J. Peter Figueroa (Chair and epidemiologist), Dr. Elizabeth Ferdinand (Public Health), Dr. Tracy Evans-Gilbert (Pediatrics and Tropical Medicine), Dr. Beryl Irons (Pediatrics and Public Health), Karen Gordon-Boyle (Program Manager, Health Sector Development CARICOM), and Ms. SueMin Nathaniel-Girdharrie (Caribbean Public Health Agency). Former members include Dr. Gabriel Gonzalez Escobar (microbiologist) and Dr. Philippe Duclos (epidemiologist; University of Geneva, Director of the ADVAC and formerly SAGE Executive Secretary); and ex-officio members Dr. Karen Lewis-Bell (former Subregional Advisor on Immunization, PAHO) and Dr. Rudolph Cummings (Program Manager, Health Sector Development, CARICOM).

  • Author contributions.
    JPF conceptualized the study. TE-G wrote the manuscript. KNL-B collected data. JPF, KNL-B, TE-G, BI, and PD developed the methodology. JPF was responsible for supervision, project administration, and funding acquisition. All authors critically reviewed and revised the manuscript and approved the final version.
  • Conflict of interest.
    None declared.
  • Funding.
    This research received a specific grant from the Pan American Health Organization for Phase 2 of this study.

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Publication Dates

  • Publication in this collection
    30 Jan 2023
  • Date of issue
    2023

History

  • Received
    31 July 2022
  • Accepted
    12 Oct 2022
Organización Panamericana de la Salud Washington - Washington - United States
E-mail: contacto_rpsp@paho.org