Completeness of tuberculosis records held on the Notifiable Health Conditions Information System (SINAN) in Santa Catarina, Brazil, 2007-2016**Article derived from the dissertation entitled ‘Diabetes mellitus as a tuberculosis case associated health condition in Santa Catarina, 2007-2016’, defended by Vanessa Baldez do Canto at the Federal University of Santa Catarina (UFSC) Public Health Postgraduate Program in 2019.

Vanessa Baldez do Canto Fúlvio Borges Nedel About the authors

Abstract

Objective

to describe the completeness of tuberculosis (TB) case records in Santa Catarina, Brazil, from 2007 to 2016.

Methods

this was a descriptive study using Notifiable Health Conditions Information System data; completeness, consistency of notification form records and timely notification were analyzed in order to assess data quality.

Results

completeness of notification form mandatory fields was considered good; essential fields were less complete, in particular the ‘Schooling’ field; low completeness of follow-up sputum smear microscopy and failure to update culture tests and HIV serology tests demonstrate weaknesses in follow-up records.

Conclusion

the tuberculosis surveillance system data were considered adequate for guiding tuberculosis prevention and control actions; record monitoring and periodical evaluation, as well as adoption of strategies to improve follow-up report completeness are recommended.

Tuberculosis; Public Health Surveillance; Epidemiology; Notification; Information Systems

Introduction

Tuberculosis (TB), despite being one of mankind’s oldest diseases, continues to be considered to be a serious Public Health problem worldwide, as the communicable disease that most leads to death. Brazil is among the 30 countries with a high tuberculosis burden. This classification encompasses data on incidence, mortality and drug resistance.11. World Health Organization. Global tuberculosis report 2017 [Internet]. Geneva: World Health Organization; 2017 [cited 2020 May 22]. 147 p. Available from: https://www.who.int/tb/publications/global_report/gtbr2017_main_text.pdf?ua=1
https://www.who.int/tb/publications/glob...
In 2018, the TB incidence rate in Brazil was 34.8 cases/100,000 inhabitants, following mean annual reduction of 1.0% between 2009 and 2018.22. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Brasil livre da tuberculose: evolução dos cenários epidemiológicos e operacionais da doença. Bol Epidemiol [Internet]. 2019 mar [citado 2020 maio 22];50(9):1-18. Disponível em: https://www.saude.gov.br/images/pdf/2019/marco/22/2019-009.pdf
https://www.saude.gov.br/images/pdf/2019...
These results are however insufficient for meeting the targets of the End Tuberculosis Strategy, an agenda approved by the World Health Assembly in 2014, when the objective of eliminating TB was a Public Health problem worldwide was defined, based on the following targets: (i) tuberculosis incidence below 10/100,000 inhab. by 2035, (ii) TB deaths reduced by 95% by 2035, in relation to TB deaths in 2015.33. World Health Organization. The end TB strategy [Internet]. Geneva; World Health Organization; 2015 [cited 2020 May 22]. Available from: https://www.who.int/tb/post2015_strategy/en/
https://www.who.int/tb/post2015_strategy...

The TB incident rate varies greatly between the Brazilian states. In 2018, Santa Catarina had 23.7 cases/100,000 inhab., which was lower than the national rate.33. World Health Organization. The end TB strategy [Internet]. Geneva; World Health Organization; 2015 [cited 2020 May 22]. Available from: https://www.who.int/tb/post2015_strategy/en/
https://www.who.int/tb/post2015_strategy...
Its neighboring states, Paraná and Rio Grande do Sul, had rates of 19.7 and 40 cases/100,000 inhab. respectively.22. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Brasil livre da tuberculose: evolução dos cenários epidemiológicos e operacionais da doença. Bol Epidemiol [Internet]. 2019 mar [citado 2020 maio 22];50(9):1-18. Disponível em: https://www.saude.gov.br/images/pdf/2019/marco/22/2019-009.pdf
https://www.saude.gov.br/images/pdf/2019...
Contrary to the falling trend found for Brazil as a whole, the Santa Catarina rate remained stable between 2005 and 2015.44. Secretaria de Estado de Saúde (Santa Catarina). Situação da tuberculose em Santa Catarina, 2001 – 2015. Inf Epidemiol Barriga Verde [Internet]. 2017 mar [citado 2020 maio 22];14(esp.):1-4. Disponível em: http://dive.sc.gov.br/conteudos/publicacoes/Informativo_Tuberculose-2017.pdf
http://dive.sc.gov.br/conteudos/publicac...

In order to make progress towards achieving the proposed targets, it is essential to plan actions based on knowledge of the epidemiological status of the disease. As such, TB surveillance should provide recommendations and inform decision making, whereby its attributions are (i) investigation of suspected cases, (ii) notification of confirmed cases and (iii) production of data on treatment and follow-up of confirmed cases until treatment is finalized.55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...

Tuberculosis has been a compulsorily notifiable disease in Brazil since 1998.66. Brasil. Ministério da Saúde. Portaria GM/MS nº 2325, de 08 de dezembro de 2003. Define a relação de doenças de notificação compulsória para todo território nacional [Internet]. Diário Oficial da União, Brasília (DF), 2003 dez 10 [citado 2020 maio 22];Seção 1:81. Disponível em: http://bvsms.saude.gov.br/bvs/saudelegis/gm/2003/prt2325_08_12_2003.html
http://bvsms.saude.gov.br/bvs/saudelegis...
Notification data are collected at heath establishments based on notification forms and monthly patient follow-up records. These data are then processed on the Notifiable Health Conditions Information System (SINAN).77. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Roteiro para análise da base de dados de tuberculose do sistema de informação de agravos de notificação SINAN e cálculo de indicadores básicos [Internet]. Brasília: Ministério da Saúde; 2006 [citado 2020 maio 22]. 52 p. Disponível em: http://www.saude.ba.gov.br/wp-content/uploads/2017/12/Caderno-de-analise-Tuberculose.pdf
http://www.saude.ba.gov.br/wp-content/up...

Studies have pointed to substantial challenges for TB surveillance, such as low contact investigation,88. Silva MDG, Bartholomay P, Cruz GO, Garcia PL. Avaliação da qualidade dos dados, oportunidade e aceitabilidade da vigilância da tuberculose nas microrregiões do Brasil. Ciênc Saúde Coletiva [Internet]. 2017 out [citado 2020 jan 26];22(10):3307-19. Disponível em: https://doi.org/10.1590/1413-812320172210.18032017
https://doi.org/10.1590/1413-81232017221...
high proportion of treatment dropout,33. World Health Organization. The end TB strategy [Internet]. Geneva; World Health Organization; 2015 [cited 2020 May 22]. Available from: https://www.who.int/tb/post2015_strategy/en/
https://www.who.int/tb/post2015_strategy...
poor completeness of notification form fields and precarious information on case diagnosis,88. Silva MDG, Bartholomay P, Cruz GO, Garcia PL. Avaliação da qualidade dos dados, oportunidade e aceitabilidade da vigilância da tuberculose nas microrregiões do Brasil. Ciênc Saúde Coletiva [Internet]. 2017 out [citado 2020 jan 26];22(10):3307-19. Disponível em: https://doi.org/10.1590/1413-812320172210.18032017
https://doi.org/10.1590/1413-81232017221...
follow-up and closure.88. Silva MDG, Bartholomay P, Cruz GO, Garcia PL. Avaliação da qualidade dos dados, oportunidade e aceitabilidade da vigilância da tuberculose nas microrregiões do Brasil. Ciênc Saúde Coletiva [Internet]. 2017 out [citado 2020 jan 26];22(10):3307-19. Disponível em: https://doi.org/10.1590/1413-812320172210.18032017
https://doi.org/10.1590/1413-81232017221...

Low quality information, apart from compromising adequate knowledge of case epidemiological profile, prevents evaluation of surveillance actions, since it is not possible to identify whether failure to fill in fields arises from weakness of surveillance actions or weakness in recording them.1414. Braga JU. Vigilância epidemiológica e o sistema de informação da tuberculose no Brasil, 2001-2003. Rev Saúde Pública [Internet]. 2007 set [citado 2020 jan 26];41(1):77-87. Disponível em: https://doi.org/10.1590/S0034-89102007000800011
https://doi.org/10.1590/S0034-8910200700...

Studies that evaluate SINAN TB databases focus on specific regions of the country.99. Santos NP, Lírio M, Passos LAR, Dias JP, Kritski AL, Galvão-Castro B, et al. Completude das fichas de notificações de tuberculose em cinco capitais do Brasil com elevada incidência da doença. J Bras Pneumol [Internet]. 2013 abr [citado 2020 jan 26];39(2):221-225. Disponível em: https://doi.org/10.1590/S1806-37132013000200014
https://doi.org/10.1590/S1806-3713201300...
The epidemiological bulletins prepared annually by the Ministry of Health and by the State Health Departments do not provide information on form data completeness nor on analyses of inconsistencies.

Studies conducted in Santa Catarina regarding SINAN data have not evaluated record quality.1515. Ferrer GCN, Silva RM, Ferrer KT, Traebert J. A carga de doença por tuberculose no estado de Santa Catarina. J Bras Pneumol [Internet]. 2013 jan-fev [citado 2020 jan 26];39(6):61-8. Disponível em: https://doi.org/10.1590/S1806-37132014000100009
https://doi.org/10.1590/S1806-3713201400...
No studies were found to have been conducted in Santa Catarina analyzing the quality of TB case records with regard to the filling in of form fields and follow-up records. A national study using municipal data conducted between 2001 and 2003 with the purpose of evaluating epidemiological surveillance quality, including the completeness of five notification form fields, found that Santa Catarina achieved the best levels in Brazil’s Southern region.1414. Braga JU. Vigilância epidemiológica e o sistema de informação da tuberculose no Brasil, 2001-2003. Rev Saúde Pública [Internet]. 2007 set [citado 2020 jan 26];41(1):77-87. Disponível em: https://doi.org/10.1590/S0034-89102007000800011
https://doi.org/10.1590/S0034-8910200700...

In view of the above, it is clearly important to analyze the quality of the SINAN TB database in Santa Catarina, in order to identify its status with regard to surveillance actions. The objective of this study was to describe the completeness of TB case records in Santa Catarina between 2007 and 2016.

Methods

This is a descriptive study using TB case data recorded on the Santa Catarina SINAN database for the period 2007-2016.

The state of Santa Catarina is located in Southern Brazil and has been comprised of 295 municipalities since autonomy was granted to the municipalities of Balneário Rincão and Pescaria Brava in 2013. In 2019 the state’s population was estimated to be 7,164,788 inhabitants.1717. Instituto Brasileiro de Geografia e Estatísticas - IBGE. Portal cidades e estados [Internet]. Rio de Janeiro: Instituto Brasileiro de Geografia e Estatísticas; 2020 [citado 2020 mar 21. Disponível em https://www.ibge.gov.br/cidades-e-estados/sc.html
https://www.ibge.gov.br/cidades-e-estado...

The population studied was comprised of TB cases aged 18 years old or over, resident in the state of Santa Catarina, notified on the SINAN system, with diagnosis date between January 1st 2007 and December 31st 2016. The study’s case exclusions criteria were: being under 18 years old; not being resident in the state of Santa Catarina; and diagnosis change during case investigation.

Completeness, record consistency and notification timeliness were analyzed to determine data quality. Completeness is understood to mean the proportion of non-null values of each record on an information system. Fields considered to be null or incomplete are those filled in as ‘Unknown’ and those left blank.1818. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. Brasília: Ministério da Saúde; 2011 [citado 2020 maio 22]. 284 p. Disponível em: http://bvsms.saude.gov.br/bvs/publicacoes/manual_recomendacoes_controle_tuberculose_brasil.pdf
http://bvsms.saude.gov.br/bvs/publicacoe...
The classification proposed by the Brazilian Ministry of Health was used to analyze field completeness: good completeness, when equal to or greater than 75.1%; regular, between 75.0% and 50.1%; poor, between 50.0% and 25.1%; and very poor, when equal to or less than 25.0%.55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...
Notification timeliness indicates the speed with which information is obtained in order to act,1919. World Health Organization. Communicable disease surveillance and response systems: guide to monitoring and evaluating [Internet]. Geneva: World Health Organization; 2006 [cited 2020 May 22]. Available from: https://www.who.int/csr/resources/publications/surveillance/WHO_CDS_EPR_LYO_2006_2/en/
https://www.who.int/csr/resources/public...
and in this study it was evaluated by the difference – in days – between diagnosis date and notification date.

Among the fields on the form, we selected those with variables considered to be strategic by the National Tuberculosis Control Program (PNCT):55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...

  1. Sex

  2. Age

  3. Type of Entry

  4. Race/Color (skin color)

  5. Schooling

  6. Form (clinical form of TB)

  7. HIV (human immunodeficiency virus)

  8. Associated Diseases and Conditions (acquired immunodeficiency syndrome [AIDS], alcoholism and diabetes)

  9. Sputum smear microscopy (diagnosis)

  10. Follow-up smear microscopy (sputum) performed at the 2nd, 4th and 6th months of treatment

  11. Case Closure Status

When analyzing follow-up smear microscopies, cases with the extrapulmonary clinical form of TB were excluded, as the sputum test is only performed on pulmonary TB cases. The concepts related to and the manner of filling in the notification form can be found in the Brazilian Tuberculosis Control Recommendations Manual and in the SINAN NET Data Dictionary.55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...

Analysis of essential field completeness was stratified by the state’s health regions. The health regions covered by the study are defined as per the current Regionalization Master Plan.2121. Secretaria de Estado da Saúde (Santa Catarina). Plano diretor de regionalização: PDR 2008 [Internet]. Florianópolis: Secretaria de Estado da Saúde; 2008 [citado 2013 out 27]. 136 p. Disponível em: http://www.saude.sc.gov.br/index.php/documentos/informacoes-gerais/planejamento-em-saude/instrumentos-de-gestao-estadual/plano-diretor-de-regionalizacao/2524-plano-diretor-de-regionalizacao-2008/file
http://www.saude.sc.gov.br/index.php/doc...

The records were retrieved from the Santa Catarina SINAN database on March 5th 2018, having been made available by the State Health Department after signing a Responsibility Commitment form.

During the study period, two TB notification forms were in use. Some fields of the version of the form used with effect from 2014 were included, excluded or altered, such as (i) Use of Illicit Drugs, (ii) Tobacco Smoking, (ii) Government income transfer program beneficiary, (iii) Antiretroviral Therapy during TB Treatment and (iv) Directly Observed Treatment (DOT). In view of these alterations, these fields were not analyzed.

Post-death notification consists of a tuberculosis case that had never been recorded on the SINAN system and was only discovered following death as a result of epidemiological investigation. This category was included in the ‘Type of Entry’ field on the form which came into force with effect from 2014.

For the purposes of analyzing consistency, two situations of inconsistent filling in of fields relating to the following were considered: (i) AIDS-associated condition (patient known to have AIDS) and negative HIV diagnosis; and (ii) positive first smear microscopy result and exclusive extrapulmonary form of TB.

Checking for duplicated records was done based on analysis of repeated entries focused on the following fields: Patient’s Name (encrypted using the soundex method); Date Current Treatment Started; Sex; Type of Entry; Notification Date; and Diagnosis Date.

In order to check for updating of notified cases, the percentage of filling in as ‘In Progress’ was calculated for the ‘Sputum culture’ and ‘HIV’ variables, for cases closed as ‘Cure’. The amount of unfilled in ‘Closure Status’ indicated failure to close cases in a timely manner, given that the database only contained records diagnosed as at December 2016. Considering that the database was retrieved in March 2018, 15 full months had gone by since the last diagnosis date. The deadline for closing TB case investigation is up to 90 days following the recommended period for ending treatment.77. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Roteiro para análise da base de dados de tuberculose do sistema de informação de agravos de notificação SINAN e cálculo de indicadores básicos [Internet]. Brasília: Ministério da Saúde; 2006 [citado 2020 maio 22]. 52 p. Disponível em: http://www.saude.ba.gov.br/wp-content/uploads/2017/12/Caderno-de-analise-Tuberculose.pdf
http://www.saude.ba.gov.br/wp-content/up...

Descriptive analyses were used to assess the quality of the database. All the variables were analyzed as to their completeness for each year from 2007 to 2016. Simple linear regression was used to analyze the trend of the filling in of essential fields. The Durbin-Watson (DW) test was used to verify observation autocorrelation. Statistically significant linear trend was admitted when the regression coefficient reached a p-value <0.05 and when DW reached a p-value >0.05.

The analyses were performed with the aid of the Stata statistical package (Stata Corp., College Station, United States), version 14.0. The study was approved by the Federal University of Santa Catarina Human Research Ethics Committee (CEPSH/UFSC): Opinion No. 78648417.1.0000.0121, dated November 21st 2017.

Results

Between 2007 and 2016, 22,741 TB cases were diagnosed in Santa Catarina. People under 18 years old (999), those who were not resident in the state (46) and those whose diagnosis changed during case investigation (820) were excluded from the study population, so that 20,876 cases remained for analysis. These were comprised of 16,640 new cases, 1,576 relapse cases, 1,287 returns after dropout, 1,332 transfers, 34 cases with no information on entry type and 7 post-death notifications.

There were no duplicated records in the database. No inconsistencies were found related to the ‘HIV’ field. With regard to clinical form, 55 cases (0.3%) had positive diagnosis smear microscopy and exclusive extrapulmonary clinical form, characterizing inconsistency in the ‘Form’ field.

When analyzing completeness, 99.9% of the mandatory fields were found to be filled in (Sex; Type of Entry; Form; Diagnosis Smear Microscopy; Sputum Culture; HIV).

The proportion of filling in of the essential fields (Race/Color [skin color]; Schooling; and Associated Conditions) was lower, in particular the ‘Schooling’ field with 15.2% not filled in. The ‘Closure Status’ field of the follow-up report was 99.1% filled in. The fields relating to associated conditions (alcoholism; diabetes; AIDS) were found to have an increasing filled in trend over the period; while ‘Schooling’ had a falling trend (Table 1).

Table 1
– Percentage and trend of completeness of tuberculosis notification form essential fields, Santa Catarina, 2007-2016

In the analysis by health region, four of the five essential fields analyzed were less than 91% filled in for the Greater Florianópolis and Northeast regions (Table 2). With regard to the ‘Race/Color’ field not being filled in, the Greater Florianópolis region accounted for 45.34% of non-filled in data, followed by the Northeast with 36.65% and the Middle Itajaí Valley with 6.55%. With regard to the ‘Schooling’ field, Greater Florianópolis accounted for 36.77% of non-filled in data, followed by the Northeast with 24.95and the River Itajaí Estuary region with 9.07%. As for the ‘Diabetes’ field, 49.92% of non-filled in data related to the Greater Florianópolis region, followed by the Northeast with 31.23% and the River Itajaí Estuary region with 8.45%. Regarding the ‘Alcoholism’ field, the Greater Florianópolis region accounted for 44.57% of non-filled in data, followed by the Northeast with 30.11% and the River Itajaí Estuary region with 6.31%. With regard to the ‘AIDS’ field, Greater Florianópolis accounted for 41.10% of non-filled in data, followed by the Northeast with 15.51% and the River Itajaí Estuary region with 14.34% (Table 2).

Table 2
– Percentage completeness of essential fields of the tuberculosis notification form by health region, Santa Catarina, 2007-2016

In the period analyzed, 6.12% of records had sputum culture ‘In Progress’ and 2.13% had HIV test ‘In Progress’. Fields filled in as ‘In Progress’ at the time when cases are notified can be updated as the follow-up report is filled in. With regard to cases closed as ‘Cure’ via the follow-up report, 1.84% showed the HIV result as still being ‘In Progress’ and 4.83% showed the sputum culture test as being in the same situation (Table 3).

Table 3
– Completeness of the HIVa and Culture test fields on the tuberculosis notification forms and SINAN follow-up records,b Santa Catarina, 2007-2016

Follow-up smear microscopies were less complete than diagnosis smear microscopies and percentage filling in of them decreased over the months of follow-up, reaching 29.5% non-filled in at the 6th month of treatment. Taking only cases with the pulmonary form of TB, the follow-up smear microscopies also had fields filled in as ‘Not Applicable’ and ‘Not Performed’, even though the ‘Not Applicable’ is for use only with extrapulmonary cases (Table 4).

Table 4
– Completeness of diagnosis smear microscopy and follow-up smear microscopy fields on the SINAN a tuberculosis databases, Santa Catarina, 2007-2016

In the period studied, 69.5% of cases were notified within 7 days following diagnosis. The median number of days of late notification was 0, demonstrating that half the cases were notified on the same day (50.2%). However, variability was considerable, with a 14-day interquartile range (IQR=0; Q3=14). When analyzing notification timeliness by entry type, percentage of cases notified in up to 7 days was 74.6% for new cases and 49.5% for the remaining entry types. Seven municipalities (2.4%) had no cases recorded during the period. In 88.4% of cases, notification was done in the individual’s municipality of residence.

Discussion

Completeness of the Santa Catarina tuberculosis notification form fields analyzed was considered to be good, according to Ministry of Health parameters. Fields classified as essential were less complete when compared to mandatory fields. Lower completeness of follow-up smear microscopies and failure to update fields filled in as ‘In Progress’ at the time when notification was made may indicate shortcomings in the use of the tuberculosis case follow-up records. A study conducted with SINAN data for the period 2001-2006 corroborates this finding, as it found unsatisfactory completeness (<80%) of variables relating to follow-up in Fortaleza, Salvador and Rio de Janeiro.1313. Malhão TA, Oliveira GP, Codennoti SB, Moherdaui F. Avaliação da completude do Sistema de Informação de Agravos de Notificação da Tuberculose, Brasil, 2001-2006. Epidemiol Serv Saúde [Internet]. 2010 jul-set [citado 2020 jan 26];19(3):245-56. Disponível em: http://dx.doi.org/10.5123/S1679-49742010000300007
http://dx.doi.org/10.5123/S1679-49742010...

Information system consistency, assessed in this study by means of the ‘HIV’ and ‘Form’ fields, was excellent. However, it should be noted that if the ‘AIDS’ field is filled as Yes, then SINAN automatically fills in the ‘HIV’ field as Positive.

Problems with regard to the completeness of sociodemographic variables have also been found by other studies.1010. Moreira CMM, Maciel ELN. Completude dos dados do Programa de Controle da Tuberculose no Sistema de Informação de Agravos de Notificação no Estado do Espírito Santo, Brasil: uma análise do período de 2001 a 2005. J Bras Pneumol [Internet]. 2008 abr [citado 2020 jan 26];34(4):225-229. Disponível em: https://doi.org/10.1590/S1806-37132008000400007
https://doi.org/10.1590/S1806-3713200800...
Considering that socio-economic conditions, such as low schooling levels, are associated with poorer TB outcomes, such as dropout, treatment failure and death,2222. Albuquerque MFPM, Ximenes RAA, Lucena-Silva N, Souza WV, Dantas AT, Rodrigues LC, et al. Factors associated with treatment failure, dropout, and death in a cohort of tuberculosis patients in Recife, Pernambuco, Brazil. Cad Saúde Pública [Internet]. 2007 Jul [cited 2020 Jan 27];23(7):1573-82. Available from: https://doi.org/10.1590/s0102-311x2007000700008
https://doi.org/10.1590/s0102-311x200700...
knowledge of the socio-economic conditions of TB cases is essential for analyzing the affected population.

Analysis as to information validity (where besides considering blank and ‘unknown’ fields, fields filled in as ‘In Progress’ are also considered when analyzing completeness) can suggest that these matters have not been investigated or that case follow-up reports are not being updated. In the period analyzed, on more than 50% of forms the ‘Culture’ field was filled in as ‘In Progress’ or ‘Not Performed’. Culture is a high specificity and high sensitivity TB diagnosis method. It is indicated, regardless of smear microscopy results, in cases of patients who have had prior treatment, immunosuppressed patients or those whose smear microscopy was positive at the end of the 2nd month of treatment.55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...

‘Not Performed’ or ‘In Progress’ accounted for 14.5% of records in the ‘HIV’ field. It should be noted that with effect from the new version of SINAN in 2014, cases for which ‘In Progress’ is input to the ‘HIV’ and ‘Culture’ fields are automatically altered to ‘Not Performed’ when they are closed.2020. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Dicionário de dados – SINAN NET – Versão 5.0: tuberculose [Internet]. Brasília: Ministério da Saúde; 2019 [citado 2020 mar 21]. Disponível em: http://portalsinan.saude.gov.br/tuberculose
http://portalsinan.saude.gov.br/tubercul...
In a study conducted in the state of Bahia, these codes accounted for more than 57% of records in the ‘HIV’ field.1111. Lírio M, Santos NP, Passos LAR, Kritski A, Galvão-Castro B, Grassi MFR. Completude das fichas de notificação de Tuberculose nos municípios prioritários da Bahia para controle da doença em indivíduos com HIV/AIDS. Ciênc Saúde Coletiva [Internet]. 2015 abr [citado 2020 jan 26];20(4):1143-1148. Disponível em: https://doi.org/10.1590/1413-81232015204.00672014
https://doi.org/10.1590/1413-81232015204...
Sanchez et al. reported that HIV serology was unavailable for 32% of TB cases notified in Brazil between 2003 and 2008,2323. Sanchez M, Bartholomay P, Arakaki-Sanchez D, Enarson D, Bissell K, Barreira D, et al. Outcomes of TB treatment by HIV status in national recording systems in Brazil, 2003-2008. PLoS One [Internet]. 201 Mar [cited 2020 Jan 27];7(3):e33129. Available from: https://doi.org/10.1371/journal.pone.0033129
https://doi.org/10.1371/journal.pone.003...
even though offering HIV testing for all TB cases has been recommended since 1998.2424. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. CoinfeçãoTB-HIV no Brasil: panorama epidemiológico e atividades colaborativas 2017. Bol Epidemiol [Internet]. 2017 jun [citado 2020 maio 22]. Disponível em: http://www.aids.gov.br/pt-br/pub/2017/coinfeccao-tb-hiv-no-brasil-panorama-epidemiologico-e-atividades-colaborativas-2017
http://www.aids.gov.br/pt-br/pub/2017/co...

The difference found between the completeness of the ‘HIV’ and ‘AIDS’ fields may be related to the guidelines for filling in the forms: filling in the ‘HIV’ field is mandatory when recording notifications on SINAN.77. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Roteiro para análise da base de dados de tuberculose do sistema de informação de agravos de notificação SINAN e cálculo de indicadores básicos [Internet]. Brasília: Ministério da Saúde; 2006 [citado 2020 maio 22]. 52 p. Disponível em: http://www.saude.ba.gov.br/wp-content/uploads/2017/12/Caderno-de-analise-Tuberculose.pdf
http://www.saude.ba.gov.br/wp-content/up...
We recommend that technical documents relating the classification of mandatory variables on SINAN be revised, as a strategy aimed at increasing the completeness of non-mandatory fields. Of the 4,989 HIV positive cases, 90.1% were recorded with AIDS as an associated condition. This indicates untreated HIV leading to AIDS and, consequently, lower immunity.2020. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Dicionário de dados – SINAN NET – Versão 5.0: tuberculose [Internet]. Brasília: Ministério da Saúde; 2019 [citado 2020 mar 21]. Disponível em: http://portalsinan.saude.gov.br/tuberculose
http://portalsinan.saude.gov.br/tubercul...
Within this context, TB and HIV/AIDS control programs at the three levels of government should implement strategies to expand health care in this population, given that the risk of an unfavorable outcome (dropout, relapse, death) is approximately three times greater in patients with TB/AIDS coinfection.2323. Sanchez M, Bartholomay P, Arakaki-Sanchez D, Enarson D, Bissell K, Barreira D, et al. Outcomes of TB treatment by HIV status in national recording systems in Brazil, 2003-2008. PLoS One [Internet]. 201 Mar [cited 2020 Jan 27];7(3):e33129. Available from: https://doi.org/10.1371/journal.pone.0033129
https://doi.org/10.1371/journal.pone.003...

Completeness quality of the diagnosis smear microscopy field was found to be good. However, analysis of smear microscopies on the follow-up reports found that percentage completeness reduced.

A study conducted in urban centers with higher TB loads in Brazil identified that between 2001 and 2006, smear microscopy at the 2nd, 4th and 6th months was among the variables with the lowest proportion of completeness. That study’s authors suggest that this fact may indicate, apart from shortcomings in filling in the forms, lack of TB case follow-up by health teams.1313. Malhão TA, Oliveira GP, Codennoti SB, Moherdaui F. Avaliação da completude do Sistema de Informação de Agravos de Notificação da Tuberculose, Brasil, 2001-2006. Epidemiol Serv Saúde [Internet]. 2010 jul-set [citado 2020 jan 26];19(3):245-56. Disponível em: http://dx.doi.org/10.5123/S1679-49742010000300007
http://dx.doi.org/10.5123/S1679-49742010...
The Ministry of Health recommends monthly smear microscopy for pulmonary TB cases and that it is essential at the 2nd, 4th and 6th months. In view of the hypotheses raised by the study mentioned above, we recommend that cross-sectional studies be conducted to analyze case follow-up, as well as the recording of information about follow-up.

Timeliness of the surveillance system revealed good ability in obtaining information, with 69.5% of cases notified within 7 days following diagnosis. This result is in agreement with Ministry of Health recommendations.1818. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. Brasília: Ministério da Saúde; 2011 [citado 2020 maio 22]. 284 p. Disponível em: http://bvsms.saude.gov.br/bvs/publicacoes/manual_recomendacoes_controle_tuberculose_brasil.pdf
http://bvsms.saude.gov.br/bvs/publicacoe...
50.2% of cases were notified on the same day they were diagnosed. A study conducted in Brazil for the period from 2005 to 2008, revealed that around 55% of TB cases were notified on the same day they were diagnosed, indicating that the country’s TB surveillance system is timely with regard to case notification.2525. Mandacarú PMP. Oportunidade do sistema de vigilância da dengue, doenças exantemáticas, meningite e tuberculose no Brasil [dissertação]. Goiânia (GO): Universidade Federal de Goiás; 2012. Disponível em: https://repositorio.bc.ufg.br/tede/handle/tede/3568
https://repositorio.bc.ufg.br/tede/handl...

Not filling in certain fields may be related to the perception of some health workers that notification forms are a merely bureaucratic matter, disregarding production of data and information as being necessary for managing health actions and services.99. Santos NP, Lírio M, Passos LAR, Dias JP, Kritski AL, Galvão-Castro B, et al. Completude das fichas de notificações de tuberculose em cinco capitais do Brasil com elevada incidência da doença. J Bras Pneumol [Internet]. 2013 abr [citado 2020 jan 26];39(2):221-225. Disponível em: https://doi.org/10.1590/S1806-37132013000200014
https://doi.org/10.1590/S1806-3713201300...
In addition, a study conducted in five Brazilian municipalities in 2011 found weaknesses in the training of TB surveillance personnel.2626. Scatena LM, Wysocki AD, Beraldo AA, Magnabosco GT, Brunello MEF, Rufino Netto A, et al. Validação e confiabilidade: instrumento para avaliação de serviços que tratam tuberculose. Rev Saúde Pública [Internet]. 2015 fev [citado 2020 jan 26];49(7):1-11. Disponível em: http://dx.doi.org/10.1590/S0034-8910.2015049005548
http://dx.doi.org/10.1590/S0034-8910.201...
In view of this, we suggest that studies be conducted capable of identifying gaps in the knowledge and competence of health workers with regard to surveillance records, with the aim of informing as to actions needed to improve notification. Changing this reality will enable programs to strengthen, as part of their routines, practices in keeping with those recommended by the PNCT, such as database linkage and analysis of data completeness and consistency.88. Silva MDG, Bartholomay P, Cruz GO, Garcia PL. Avaliação da qualidade dos dados, oportunidade e aceitabilidade da vigilância da tuberculose nas microrregiões do Brasil. Ciênc Saúde Coletiva [Internet]. 2017 out [citado 2020 jan 26];22(10):3307-19. Disponível em: https://doi.org/10.1590/1413-812320172210.18032017
https://doi.org/10.1590/1413-81232017221...

Over 10% of cases were notified in municipalities different to the municipality of residence. In order to improve the TB surveillance system, both with regard to case detection and also case follow-up, Primary Care needs to be strengthened and its responsibilities in controlling TB need to be made effective, especially identification of symptomatic respiratory cases, active tracing of dropout cases, as well as case treatment and follow-up. The Ministry of Health sees the National Health System (SUS), particularly the Family Health Strategy (ESF), as the main entry point to the Public Health system for symptomatic respiratory cases and people with TB. Primary Health Care attributes promote stronger links between patients and health workers and thus favor activities such as active tracing, contact investigation, directly observed treatment (DOT) and case follow-up.2727. Cardozo-Gonzales RI, Palha PF, Harter J, Alarcon E, Lima LM, Tomberg JO. Avaliação das ações de detecção de casos de tuberculose na atenção primária. Rev Eletrônica Enferm [Internet]. 2015 out-dez [citado 2020 jan 26];17(4). Disponível em: https://doi.org/10.5216/ree.v17i4.32846
https://doi.org/10.5216/ree.v17i4.32846...
Increased ESF team coverage in Curitiba between 2000 and 2009, for instance, was associated with a reduction in the proportion of TB treatment dropout.2828. Marquieviz J, Alves IS, Neves EB, Ulbricht L. A estratégia de saúde da família no controle da tuberculose em Curitiba (PR). Ciên Saúde Coletiva [Internet]. 2013 jan [citado 2020 jan 26];18(1):265-71. Disponível em: http://dx.doi.org/10.1590/S1413-81232013000100027
http://dx.doi.org/10.1590/S1413-81232013...

We recommend the establishment of targets for the State Plan to Combat TB, in order to enhance record quality and to return to having TB indicators in agreements between SUS levels, with the aim of reviewing the TB surveillance system. During the study period, seven Santa Catarina municipalities (São João do Oeste, Palma Sola, Sul Brasil, Águas de Chapecó, Cunhataí, Urupema and Marema) had no TB cases among their residents. They are municipalities with fewer than 10,000 inhabitants – four of them have fewer than 3,000 inhabitants –, located in regions with high TB rates. It is important to highlight that municipalities with no cases, located in areas of high risk of TB occurrence, need to be analyzed with caution, in view of the possibility of underreporting.2929. Oliveira GP, Pinheiro RS, Coeli CM, Barreira D, Codenotti SB. Uso do sistema de informação sobre mortalidade para identificar subnotificação de casos de tuberculose no Brasil. Rev Bras Epidemiol [Internet]. 2012 set [citado 2020 jan 26];15(3):468-77. Disponível em: http://dx.doi.org/10.1590/S1415-790X2012000300003
http://dx.doi.org/10.1590/S1415-790X2012...
In cases such as these, monitoring of the proportion of symptomatic respiratory cases and contacts examined is recommended, in order to evaluate the quality of municipal surveillance systems with regard to case detection. Carrying out population and health service surveys to identify symptomatic respiratory cases can assist in analyzing shortcomings in case detection.

Periodical checking of data completeness should be part of municipal surveillance actions, as well as analysis of inconsistency and duplicated records, as per Ministry of Health recommendations.55. Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
http://dive.sc.gov.br/conteudos/agravos/...

The results of this study have enabled a panorama to be drawn of TB notification records in Santa Catarina. The Greater Florianópolis health region contributed most to essential fields not being filled in. This shows that specific attention needs to be paid to notification records in that region. Overall, the TB surveillance system data were adequate for guiding TB prevention and control actions. Nevertheless, they can be improved. In the period assessed, the fields relating to associated conditions (alcoholism, diabetes and AIDS) showed increased completeness, while completeness of the ‘Schooling’ field decreased, and completeness of the ‘Race/Skin Color’ field remained stable. Weaknesses were demonstrated in notification records and follow-up records.

This study provides original information for TB surveillance in the state of Santa Catarina, serving to inform health service managers and workers, both at state and municipal level, for making joint decisions seeking to improve health team work processes and improve information on tuberculosis, thus contributing to its control.

References

  • 1
    World Health Organization. Global tuberculosis report 2017 [Internet]. Geneva: World Health Organization; 2017 [cited 2020 May 22]. 147 p. Available from: https://www.who.int/tb/publications/global_report/gtbr2017_main_text.pdf?ua=1
    » https://www.who.int/tb/publications/global_report/gtbr2017_main_text.pdf?ua=1
  • 2
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Brasil livre da tuberculose: evolução dos cenários epidemiológicos e operacionais da doença. Bol Epidemiol [Internet]. 2019 mar [citado 2020 maio 22];50(9):1-18. Disponível em: https://www.saude.gov.br/images/pdf/2019/marco/22/2019-009.pdf
    » https://www.saude.gov.br/images/pdf/2019/marco/22/2019-009.pdf
  • 3
    World Health Organization. The end TB strategy [Internet]. Geneva; World Health Organization; 2015 [cited 2020 May 22]. Available from: https://www.who.int/tb/post2015_strategy/en/
    » https://www.who.int/tb/post2015_strategy/en/
  • 4
    Secretaria de Estado de Saúde (Santa Catarina). Situação da tuberculose em Santa Catarina, 2001 – 2015. Inf Epidemiol Barriga Verde [Internet]. 2017 mar [citado 2020 maio 22];14(esp.):1-4. Disponível em: http://dive.sc.gov.br/conteudos/publicacoes/Informativo_Tuberculose-2017.pdf
    » http://dive.sc.gov.br/conteudos/publicacoes/Informativo_Tuberculose-2017.pdf
  • 5
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. 2. ed. Brasília: Ministério da Saúde; 2019 [citado 2020 maio 22]. 364 p. Disponível em: http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
    » http://dive.sc.gov.br/conteudos/agravos/publicacoes/manual-recomendacoestuberculose-20mar19-isbn.pdf
  • 6
    Brasil. Ministério da Saúde. Portaria GM/MS nº 2325, de 08 de dezembro de 2003. Define a relação de doenças de notificação compulsória para todo território nacional [Internet]. Diário Oficial da União, Brasília (DF), 2003 dez 10 [citado 2020 maio 22];Seção 1:81. Disponível em: http://bvsms.saude.gov.br/bvs/saudelegis/gm/2003/prt2325_08_12_2003.html
    » http://bvsms.saude.gov.br/bvs/saudelegis/gm/2003/prt2325_08_12_2003.html
  • 7
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Roteiro para análise da base de dados de tuberculose do sistema de informação de agravos de notificação SINAN e cálculo de indicadores básicos [Internet]. Brasília: Ministério da Saúde; 2006 [citado 2020 maio 22]. 52 p. Disponível em: http://www.saude.ba.gov.br/wp-content/uploads/2017/12/Caderno-de-analise-Tuberculose.pdf
    » http://www.saude.ba.gov.br/wp-content/uploads/2017/12/Caderno-de-analise-Tuberculose.pdf
  • 8
    Silva MDG, Bartholomay P, Cruz GO, Garcia PL. Avaliação da qualidade dos dados, oportunidade e aceitabilidade da vigilância da tuberculose nas microrregiões do Brasil. Ciênc Saúde Coletiva [Internet]. 2017 out [citado 2020 jan 26];22(10):3307-19. Disponível em: https://doi.org/10.1590/1413-812320172210.18032017
    » https://doi.org/10.1590/1413-812320172210.18032017
  • 9
    Santos NP, Lírio M, Passos LAR, Dias JP, Kritski AL, Galvão-Castro B, et al. Completude das fichas de notificações de tuberculose em cinco capitais do Brasil com elevada incidência da doença. J Bras Pneumol [Internet]. 2013 abr [citado 2020 jan 26];39(2):221-225. Disponível em: https://doi.org/10.1590/S1806-37132013000200014
    » https://doi.org/10.1590/S1806-37132013000200014
  • 10
    Moreira CMM, Maciel ELN. Completude dos dados do Programa de Controle da Tuberculose no Sistema de Informação de Agravos de Notificação no Estado do Espírito Santo, Brasil: uma análise do período de 2001 a 2005. J Bras Pneumol [Internet]. 2008 abr [citado 2020 jan 26];34(4):225-229. Disponível em: https://doi.org/10.1590/S1806-37132008000400007
    » https://doi.org/10.1590/S1806-37132008000400007
  • 11
    Lírio M, Santos NP, Passos LAR, Kritski A, Galvão-Castro B, Grassi MFR. Completude das fichas de notificação de Tuberculose nos municípios prioritários da Bahia para controle da doença em indivíduos com HIV/AIDS. Ciênc Saúde Coletiva [Internet]. 2015 abr [citado 2020 jan 26];20(4):1143-1148. Disponível em: https://doi.org/10.1590/1413-81232015204.00672014
    » https://doi.org/10.1590/1413-81232015204.00672014
  • 12
    Medeiros D, Sucupira DE, Guedes RM, Costa AJL. Análise da qualidade das informações sobre tuberculose no município de Belford Roxo, Rio de Janeiro, 2006 a 2008. Cad Saúde Colet [Internet]. 2012 abr [citado 2020 jan 26];20(2):146-52. Disponível em: http://www.cadernos.iesc.ufrj.br/cadernos/images/csc/2012_2/artigos/csc_v20n2_146-152.pdf
    » http://www.cadernos.iesc.ufrj.br/cadernos/images/csc/2012_2/artigos/csc_v20n2_146-152.pdf
  • 13
    Malhão TA, Oliveira GP, Codennoti SB, Moherdaui F. Avaliação da completude do Sistema de Informação de Agravos de Notificação da Tuberculose, Brasil, 2001-2006. Epidemiol Serv Saúde [Internet]. 2010 jul-set [citado 2020 jan 26];19(3):245-56. Disponível em: http://dx.doi.org/10.5123/S1679-49742010000300007
    » http://dx.doi.org/10.5123/S1679-49742010000300007
  • 14
    Braga JU. Vigilância epidemiológica e o sistema de informação da tuberculose no Brasil, 2001-2003. Rev Saúde Pública [Internet]. 2007 set [citado 2020 jan 26];41(1):77-87. Disponível em: https://doi.org/10.1590/S0034-89102007000800011
    » https://doi.org/10.1590/S0034-89102007000800011
  • 15
    Ferrer GCN, Silva RM, Ferrer KT, Traebert J. A carga de doença por tuberculose no estado de Santa Catarina. J Bras Pneumol [Internet]. 2013 jan-fev [citado 2020 jan 26];39(6):61-8. Disponível em: https://doi.org/10.1590/S1806-37132014000100009
    » https://doi.org/10.1590/S1806-37132014000100009
  • 16
    Mendonça SA, Franco SC. Avaliação do risco epidemiológico e do desempenho dos programas de controle de tuberculose nas Regiões de Saúde do estado de Santa Catarina, 2003 a 2010. Epidemiol Serv Saúde [Internet]. 2015 jan-mar [citado 2020 jan 26];24(1):59-70. Disponível em: https://doi.org/10.5123/S1679-49742015000100007
    » https://doi.org/10.5123/S1679-49742015000100007
  • 17
    Instituto Brasileiro de Geografia e Estatísticas - IBGE. Portal cidades e estados [Internet]. Rio de Janeiro: Instituto Brasileiro de Geografia e Estatísticas; 2020 [citado 2020 mar 21. Disponível em https://www.ibge.gov.br/cidades-e-estados/sc.html
    » https://www.ibge.gov.br/cidades-e-estados/sc.html
  • 18
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Manual de recomendações para o controle da tuberculose no Brasil [Internet]. Brasília: Ministério da Saúde; 2011 [citado 2020 maio 22]. 284 p. Disponível em: http://bvsms.saude.gov.br/bvs/publicacoes/manual_recomendacoes_controle_tuberculose_brasil.pdf
    » http://bvsms.saude.gov.br/bvs/publicacoes/manual_recomendacoes_controle_tuberculose_brasil.pdf
  • 19
    World Health Organization. Communicable disease surveillance and response systems: guide to monitoring and evaluating [Internet]. Geneva: World Health Organization; 2006 [cited 2020 May 22]. Available from: https://www.who.int/csr/resources/publications/surveillance/WHO_CDS_EPR_LYO_2006_2/en/
    » https://www.who.int/csr/resources/publications/surveillance/WHO_CDS_EPR_LYO_2006_2/en/
  • 20
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. Dicionário de dados – SINAN NET – Versão 5.0: tuberculose [Internet]. Brasília: Ministério da Saúde; 2019 [citado 2020 mar 21]. Disponível em: http://portalsinan.saude.gov.br/tuberculose
    » http://portalsinan.saude.gov.br/tuberculose
  • 21
    Secretaria de Estado da Saúde (Santa Catarina). Plano diretor de regionalização: PDR 2008 [Internet]. Florianópolis: Secretaria de Estado da Saúde; 2008 [citado 2013 out 27]. 136 p. Disponível em: http://www.saude.sc.gov.br/index.php/documentos/informacoes-gerais/planejamento-em-saude/instrumentos-de-gestao-estadual/plano-diretor-de-regionalizacao/2524-plano-diretor-de-regionalizacao-2008/file
    » http://www.saude.sc.gov.br/index.php/documentos/informacoes-gerais/planejamento-em-saude/instrumentos-de-gestao-estadual/plano-diretor-de-regionalizacao/2524-plano-diretor-de-regionalizacao-2008/file
  • 22
    Albuquerque MFPM, Ximenes RAA, Lucena-Silva N, Souza WV, Dantas AT, Rodrigues LC, et al. Factors associated with treatment failure, dropout, and death in a cohort of tuberculosis patients in Recife, Pernambuco, Brazil. Cad Saúde Pública [Internet]. 2007 Jul [cited 2020 Jan 27];23(7):1573-82. Available from: https://doi.org/10.1590/s0102-311x2007000700008
    » https://doi.org/10.1590/s0102-311x2007000700008
  • 23
    Sanchez M, Bartholomay P, Arakaki-Sanchez D, Enarson D, Bissell K, Barreira D, et al. Outcomes of TB treatment by HIV status in national recording systems in Brazil, 2003-2008. PLoS One [Internet]. 201 Mar [cited 2020 Jan 27];7(3):e33129. Available from: https://doi.org/10.1371/journal.pone.0033129
    » https://doi.org/10.1371/journal.pone.0033129
  • 24
    Ministério da Saúde (BR). Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica. CoinfeçãoTB-HIV no Brasil: panorama epidemiológico e atividades colaborativas 2017. Bol Epidemiol [Internet]. 2017 jun [citado 2020 maio 22]. Disponível em: http://www.aids.gov.br/pt-br/pub/2017/coinfeccao-tb-hiv-no-brasil-panorama-epidemiologico-e-atividades-colaborativas-2017
    » http://www.aids.gov.br/pt-br/pub/2017/coinfeccao-tb-hiv-no-brasil-panorama-epidemiologico-e-atividades-colaborativas-2017
  • 25
    Mandacarú PMP. Oportunidade do sistema de vigilância da dengue, doenças exantemáticas, meningite e tuberculose no Brasil [dissertação]. Goiânia (GO): Universidade Federal de Goiás; 2012. Disponível em: https://repositorio.bc.ufg.br/tede/handle/tede/3568
    » https://repositorio.bc.ufg.br/tede/handle/tede/3568
  • 26
    Scatena LM, Wysocki AD, Beraldo AA, Magnabosco GT, Brunello MEF, Rufino Netto A, et al. Validação e confiabilidade: instrumento para avaliação de serviços que tratam tuberculose. Rev Saúde Pública [Internet]. 2015 fev [citado 2020 jan 26];49(7):1-11. Disponível em: http://dx.doi.org/10.1590/S0034-8910.2015049005548
    » http://dx.doi.org/10.1590/S0034-8910.2015049005548
  • 27
    Cardozo-Gonzales RI, Palha PF, Harter J, Alarcon E, Lima LM, Tomberg JO. Avaliação das ações de detecção de casos de tuberculose na atenção primária. Rev Eletrônica Enferm [Internet]. 2015 out-dez [citado 2020 jan 26];17(4). Disponível em: https://doi.org/10.5216/ree.v17i4.32846
    » https://doi.org/10.5216/ree.v17i4.32846
  • 28
    Marquieviz J, Alves IS, Neves EB, Ulbricht L. A estratégia de saúde da família no controle da tuberculose em Curitiba (PR). Ciên Saúde Coletiva [Internet]. 2013 jan [citado 2020 jan 26];18(1):265-71. Disponível em: http://dx.doi.org/10.1590/S1413-81232013000100027
    » http://dx.doi.org/10.1590/S1413-81232013000100027
  • 29
    Oliveira GP, Pinheiro RS, Coeli CM, Barreira D, Codenotti SB. Uso do sistema de informação sobre mortalidade para identificar subnotificação de casos de tuberculose no Brasil. Rev Bras Epidemiol [Internet]. 2012 set [citado 2020 jan 26];15(3):468-77. Disponível em: http://dx.doi.org/10.1590/S1415-790X2012000300003
    » http://dx.doi.org/10.1590/S1415-790X2012000300003

  • *
    Article derived from the dissertation entitled ‘Diabetes mellitus as a tuberculosis case associated health condition in Santa Catarina, 2007-2016’, defended by Vanessa Baldez do Canto at the Federal University of Santa Catarina (UFSC) Public Health Postgraduate Program in 2019.

Publication Dates

  • Publication in this collection
    08 July 2020
  • Date of issue
    2020

History

  • Received
    28 Jan 2020
  • Accepted
    11 May 2020
Secretaria de Vigilância em Saúde - Ministério da Saúde do Brasil Brasília - Distrito Federal - Brazil
E-mail: leilapgarcia@gmail.com